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Yaron Carmi

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Recent Articles
1.
Camargo S, Moskowitz O, Giladi A, Levinson M, Balaban R, Gola S, et al.
Nat Cancer . 2025 Mar; PMID: 40055573
Tissue remodeling and cell plasticity in the mammary gland are activated by multilineage communications; however, the dynamic signaling promoting breast cancer remains unclear. Here, by RNA sequencing of single cells...
2.
Maliah A, Santana-Magal N, Parikh S, Gordon S, Reshef K, Sade Y, et al.
Nat Commun . 2024 Sep; 15(1):8354. PMID: 39333093
T cell inhibitory mechanisms prevent autoimmune reactions, while cancer immunotherapy aims to remove these inhibitory signals. Chronic ultraviolet (UV) exposure attenuates autoimmunity through promotion of poorly understood immune-suppressive mechanisms. Here...
3.
Farhat-Younis L, Na M, Zarfin A, Khateeb A, Santana-Magal N, Richter A, et al.
Elife . 2024 Jul; 13. PMID: 38953289
No abstract available.
4.
Farhat-Younis L, Na M, Zarfin A, Khateeb A, Santana-Magal N, Richter A, et al.
Elife . 2024 Jun; 12. PMID: 38885133
Despite the central role of T cells in tumor immunity, attempts to harness their cytotoxic capacity as a therapy have met limited efficacy, partially as a result of the suppressive...
5.
Parikh R, Parikh S, Berzin D, Vaknine H, Ovadia S, Likonen D, et al.
EMBO J . 2024 May; 43(17):3553-3586. PMID: 38719996
Extracellular vesicles (EVs) are important mediators of communication between cells. Here, we reveal a new mode of intercellular communication by melanosomes, large EVs secreted by melanocytes for melanin transport. Unlike...
6.
Allen B, Hiam K, Burnett C, Venida A, DeBarge R, Tenvooren I, et al.
Nat Med . 2024 Apr; 30(5):1502. PMID: 38565647
No abstract available.
7.
Rasoulouniriana D, Santana-Magal N, Gutwillig A, Farhat-Younis L, Tal L, Amar S, et al.
Cancer Immunol Res . 2023 Apr; 11(6):792-809. PMID: 37070661
The pioneering design of chimeric antigen receptor (CAR) T-cell therapy demonstrated the potential of reprogramming the immune system. Nonetheless, T-cell exhaustion, toxicity, and suppressive microenvironments limit their efficacy in solid...
8.
Gutwillig A, Santana-Magal N, Farhat-Younis L, Rasoulouniriana D, Madi A, Luxenburg C, et al.
Elife . 2022 Sep; 11. PMID: 36124553
Despite the remarkable successes of cancer immunotherapies, the majority of patients will experience only partial response followed by relapse of resistant tumors. While treatment resistance has frequently been attributed to...
9.
Nahmad A, Lazzarotto C, Zelikson N, Kustin T, Tenuta M, Huang D, et al.
Nat Biotechnol . 2022 Jun; 40(8):1241-1249. PMID: 35681059
Transplantation of B cells engineered ex vivo to secrete broadly neutralizing antibodies (bNAbs) has shown efficacy in disease models. However, clinical translation of this approach would require specialized medical centers,...
10.
Gross G, Carmi Y, Abken H
Front Immunol . 2022 May; 13:902594. PMID: 35572501
No abstract available.