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Yaohang Li

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Articles 67
Citations 852
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Recent Articles
1.
Guo F, Guan R, Li Y, Liu Q, Wang X, Yang C, et al.
Natl Sci Rev . 2025 Mar; 12(4):nwaf028. PMID: 40078374
With the adoption of foundation models (FMs), artificial intelligence (AI) has become increasingly significant in bioinformatics and has successfully addressed many historical challenges, such as pre-training frameworks, model evaluation and...
2.
Xu Y, Wang S, Feng Q, Xia J, Li Y, Li H, et al.
Nat Commun . 2024 Aug; 15(1):7561. PMID: 39215003
Single-cell RNA sequencing (scRNA-seq) technologies have become essential tools for characterizing cellular landscapes within complex tissues. Large-scale single-cell transcriptomics holds great potential for identifying rare cell types critical to the...
3.
Hu K, Ni P, Xu M, Zou Y, Chang J, Gao X, et al.
Nat Commun . 2024 Jul; 15(1):5573. PMID: 38956036
Recent advancements in genome assembly have greatly improved the prospects for comprehensive annotation of Transposable Elements (TEs). However, existing methods for TE annotation using genome assemblies suffer from limited accuracy...
4.
Deng C, Li H, Zhang L, Liu Y, Li Y, Wang J
Bioinformatics . 2024 Jun; 40(Suppl 1):i511-i520. PMID: 38940121
Motivation: Identifying cancer genes remains a significant challenge in cancer genomics research. Annotated gene sets encode functional associations among multiple genes, and cancer genes have been shown to cluster in...
5.
Wang M, Lei C, Wang J, Li Y, Li M
Brief Bioinform . 2024 Apr; 25(3). PMID: 38600667
Human leukocyte antigen (HLA) recognizes foreign threats and triggers immune responses by presenting peptides to T cells. Computationally modeling the binding patterns between peptide and HLA is very important for...
6.
Zhao H, Ni P, Zhao Q, Liang X, Ai D, Erhardt S, et al.
Commun Biol . 2023 Aug; 6(1):870. PMID: 37620651
Adverse Drug Reactions (ADRs) have a direct impact on human health. As continuous pharmacovigilance and drug monitoring prove to be costly and time-consuming, computational methods have emerged as promising alternatives....
7.
Zhao H, Zhang X, Zhao Q, Li Y, Wang J
Bioinformatics . 2023 Aug; 39(9). PMID: 37606993
Motivation: Cancer heterogeneity drastically affects cancer therapeutic outcomes. Predicting drug response in vitro is expected to help formulate personalized therapy regimens. In recent years, several computational models based on machine...
8.
Xu Y, Li H, Lin C, Zheng R, Li Y, Xu J, et al.
Bioinformatics . 2023 Jun; 39(39 Suppl 1):i368-i376. PMID: 37387178
Motivation: Single-cell RNA sequencing (scRNA-seq) offers a powerful tool to dissect the complexity of biological tissues through cell sub-population identification in combination with clustering approaches. Feature selection is a critical...
9.
Niu K, Wu Y, Li Y, Li M
J Biomed Inform . 2023 May; 143:104396. PMID: 37211195
Automated ICD coding is a multi-label prediction task aiming at assigning patient diagnoses with the most relevant subsets of disease codes. In the deep learning regime, recent works have suffered...
10.
Wang B, Liu K, Li Y, Wang J
Bioinformatics . 2023 Apr; 39(5). PMID: 37084258
Motivation: Hi-C technology has been the most widely used chromosome conformation capture (3C) experiment that measures the frequency of all paired interactions in the entire genome, which is a powerful...