Yannick Simoni
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Explore the profile of Yannick Simoni including associated specialties, affiliations and a list of published articles.
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35
Citations
2058
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Recent Articles
1.
Ye L, Ryu H, Granadier D, Nguyen L, Simoni Y, Dick I, et al.
Transl Lung Cancer Res
. 2024 Oct;
13(9):2352-2372.
PMID: 39430319
Background: Anti-tumor CD8 T cells are important for immunity but can become 'exhausted' and hence ineffective. Tumor-infiltrating exhausted CD8 T cells include less differentiated stem-like exhausted T (Tex) cells and...
2.
Tentori C, Zhao L, Tinterri B, Strange K, Zoldan K, Dimopoulos K, et al.
Hemasphere
. 2024 May;
8(5):e64.
PMID: 38756352
Advancements in comprehending myelodysplastic neoplasms (MDS) have unfolded significantly in recent years, elucidating a myriad of cellular and molecular underpinnings integral to disease progression. While molecular inclusions into prognostic models...
3.
Schmidt F, Fields H, Purwanti Y, Milojkovic A, Salim S, Wu K, et al.
Cell Rep
. 2023 Oct;
42(10):113250.
PMID: 37837618
Following viral infection, the human immune system generates CD8 T cell responses to virus antigens that differ in specificity, abundance, and phenotype. A characterization of virus-specific T cell responses allows...
4.
Li S, Zhuang S, Heit A, Koo S, Tan A, Chow I, et al.
Oncoimmunology
. 2022 Dec;
11(1):2012961.
PMID: 36524209
Tumor-specific T cells likely underpin effective immune checkpoint-blockade therapies. Yet, most studies focus on Treg cells and CD8 tumor-infiltrating lymphocytes (TILs). Here, we study CD4 TILs in human lung and...
5.
Simoni Y, Chapuis N
Diagnostics (Basel)
. 2022 Jul;
12(7).
PMID: 35885563
Myelodysplastic syndromes (MDS) constitute a very heterogeneous group of diseases with a high prevalence in elderly patients and a propensity for progression to acute myeloid leukemia. The complexity of these...
6.
Ishihara M, Kitano S, Kageyama S, Miyahara Y, Yamamoto N, Kato H, et al.
J Immunother Cancer
. 2022 Jun;
10(6).
PMID: 35768164
Background: Because of the shortage of ideal cell surface antigens, the development of T-cell receptor (TCR)-engineered T cells (TCR-T) that target intracellular antigens such as NY-ESO-1 is a promising approach...
7.
Li S, Simoni Y, Zhuang S, Gabel A, Ma S, Chee J, et al.
Proc Natl Acad Sci U S A
. 2021 Jul;
118(30).
PMID: 34285073
Neoantigen-specific T cells are strongly implicated as being critical for effective immune checkpoint blockade treatment (ICB) (e.g., anti-PD-1 and anti-CTLA-4) and are being targeted for vaccination-based therapies. However, ICB treatments...
8.
Yeong J, Suteja L, Simoni Y, Lau K, Tan A, Li H, et al.
J Thorac Oncol
. 2021 May;
16(8):1349-1358.
PMID: 33975004
Introduction: Programmed cell death protein-1 (PD-1) and programmed death-ligand 1 (PD-L1) blockade is currently widely used in the treatment of metastatic NSCLC. Despite available biomarker stratification, clinical responses vary. Thus,...
9.
Li S, Simoni Y, Becht E, Loh C, Li N, Lachance D, et al.
Cell Rep Med
. 2020 Nov;
1(3):100039.
PMID: 33205061
Growing evidence indicates a role for the gut microbiota in modulating anti-tumor treatment efficacy in human cancer. Here we study mucosa-associated invariant T (MAIT) cells to look for evidence of...
10.
Simoni Y, Becht E, Li S, Loh C, Yeong J, Lim T, et al.
Clin Transl Immunology
. 2020 Sep;
9(9):e1175.
PMID: 32995000
Objectives: Lymphoepithelioma-like carcinoma (LELC) is an uncommon lung cancer, typically observed in young, non-smoking Asian populations. LELC is associated with Epstein-Barr virus (EBV) infection of lung tumor cells of epithelial...