Yannick Jacques
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Explore the profile of Yannick Jacques including associated specialties, affiliations and a list of published articles.
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44
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1322
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Recent Articles
1.
Meghnem D, Maillasson M, Barbieux I, Morisseau S, Keita D, Jacques Y, et al.
Front Immunol
. 2022 May;
13:886213.
PMID: 35592318
Cytokines are crucial molecules for maintaining the proper functioning of the immune system. Nevertheless, a dysregulation of cytokine expression could be involved in the pathogenesis of autoimmune diseases. Interleukin (IL)-15...
2.
Vanhove B, Duvaux O, Rousse J, Royer P, Evanno G, Ciron C, et al.
bioRxiv
. 2021 May;
PMID: 34013271
Perfusion of convalescent plasma (CP) has demonstrated a potential to improve the pneumonia induced by SARS-CoV-2, but procurement and standardization of CP are barriers to its wide usage. Many monoclonal...
3.
Vanhove B, Duvaux O, Rousse J, Royer P, Evanno G, Ciron C, et al.
Eur J Immunol
. 2021 Feb;
51(6):1412-1422.
PMID: 33576494
Heterologous polyclonal antibodies might represent an alternative to the use of convalescent plasma or monoclonal antibodies (mAbs) in coronavirus disease (COVID-19) by targeting multiple antigen epitopes. However, heterologous antibodies trigger...
4.
Desbois M, Beal C, Charrier M, Besse B, Meurice G, Cagnard N, et al.
J Immunother Cancer
. 2020 Jun;
8(1).
PMID: 32532840
Background: As the immune system is compromised in patients with cancer, therapeutic strategies to stimulate immunity appear promising, to avoid relapse and increase long-term overall survival. Interleukin-15 (IL-15) has similar...
5.
IL-15Rα membrane anchorage in either or is required for stabilization of IL-15 and optimal signaling
Quemener A, Morisseau S, Sousa R, Trillet K, Maillasson M, Leray I, et al.
J Cell Sci
. 2019 Oct;
133(5).
PMID: 31653781
Interleukin (IL)-15 plays an important role in the communication between immune cells. It delivers its signal through different modes involving three receptor chains: IL-15Rα, IL-2Rβ and IL-2Rγc. The combination of...
6.
Frutoso M, Morisseau S, Tamzalit F, Quemener A, Meghnem D, Leray I, et al.
J Immunol
. 2018 Jun;
201(2):493-506.
PMID: 29848756
IL-15 is a cytokine playing a crucial role in the function of immune cells, including NK and CD8 T cells. In this study, we demonstrated that in vivo, in mice,...
7.
Quemener A, Maillasson M, Arzel L, Sicard B, Vomiandry R, Mortier E, et al.
J Med Chem
. 2017 Jun;
60(14):6249-6272.
PMID: 28657314
Interleukin (IL)-15 is a pleiotropic cytokine, which is structurally close to IL-2 and shares with it the IL-2 β and γ receptor (R) subunits. By promoting the activation and proliferation...
8.
Meghnem D, Morisseau S, Frutoso M, Trillet K, Maillasson M, Barbieux I, et al.
J Immunol
. 2017 May;
198(12):4563-4568.
PMID: 28507024
Interleukin 2 and IL-15 are two closely related cytokines, displaying important functions in the immune system. They share the heterodimeric CD122/CD132 receptor to deliver their signals within target cells. Their...
9.
Jacques Y, Mortier E
Med Sci (Paris)
. 2016 Jul;
32(6-7):612-8.
PMID: 27406772
Interleukin-2, a cytokine identified as T-cell growth factor, has long been regarded as central to the development and effector activities of immune responses. Several gene knockout mouse studies and observations...
10.
Desbois M, Vu P, Coutzac C, Marcheteau E, Beal C, Terme M, et al.
J Immunol
. 2016 May;
197(1):168-78.
PMID: 27217584
Tumors with the help of the surrounding environment facilitate the immune suppression in patients, and immunotherapy can counteract this inhibition. Among immunotherapeutic strategies, the immunostimulatory cytokine IL-15 could represent a...