Yang-Fan Guo
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Explore the profile of Yang-Fan Guo including associated specialties, affiliations and a list of published articles.
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8
Citations
24
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Recent Articles
1.
Guo Y, Xu T, Zhang G, Dong H
Molecules
. 2025 Jan;
30(1.
PMID: 39795241
In this study, we developed an indirect method for the synthesis of 2-deoxyglycosides with an exclusive β-configuration using glucosyl and galactosyl bromide donors with 2-thioacetyl (SAc) groups. The 2-SAc glucosyl...
2.
Luo T, Zhang G, Guo Y, Dong H
J Org Chem
. 2024 Sep;
89(19):14315-14327.
PMID: 39268645
In this study, we have successfully developed a glycosylation method using 1--(methylthio)thiocarbonyl-glycoses as donors. Such xanthate donors are easily accessible and shelf-stable. The glycosylation reaction could be promoted by cations...
3.
Guo Y, Yu J, Dong H
J Org Chem
. 2024 Jun;
89(12):8706-8720.
PMID: 38825808
In this study, we systematically investigated the regioselective glycosylation of 2,4-OH mannoside and galactoside acceptors since regioselective protection of their 3- and 6-OHs is readily achieved. By altering the protecting...
4.
Feng G, Guo Y, Tang Y, Li M, Jia Y, Li Z, et al.
J Med Chem
. 2023 Aug;
66(17):12536-12543.
PMID: 37608596
In this study, we have investigated the potential of two classes of thioglucoside analogues of gliflozins as antidiabetic drugs, one with substitutions of S-atoms in meta-positions (similar to -glucoside SGLT2...
5.
Luo T, Guo Y, Xu T, Dong H
J Org Chem
. 2023 May;
88(13):8024-8033.
PMID: 37226814
In this study, we have successfully applied a visible-light-promoted desulfurization method to the synthesis of deoxysugars, especially 1-deoxyglycose, 2,4-deoxyglycosides, and 2-deoxyglycosides with exclusive α-configuration. Compared to the reported desulfurization under...
6.
Luo T, Xu T, Guo Y, Dong H
Molecules
. 2022 Dec;
27(23).
PMID: 36500346
Acetalization and deacetalation are a pair of routine manipulations to protect and deprotect the 4- and 6-hydroxyl groups of glycosides in the synthesis of glycosyl building blocks. In this study,...
7.
Guo Y, Luo T, Feng G, Liu C, Dong H
Molecules
. 2022 Sep;
27(18).
PMID: 36144712
An improved method to efficiently synthesize 2-OH thioaryl glycosides starting from corresponding per-protected glycals was developed, where 1,2-anhydro sugars were prepared by the oxidation of glycals with oxone, followed by...
8.
Feng G, Luo T, Guo Y, Liu C, Dong H
J Org Chem
. 2022 Jan;
87(5):3638-3646.
PMID: 35060379
A relatively green method for synthesizing 1-thioalkyl glycosides has been developed, where sodium alkanethiolates were used to react with per-O-acetylated sugars instead of odorous alkyl mercaptans in the presence of...
9.
Yang Z, Huang S, Chen L, Liu F, Cai X, Guo Y, et al.
J Clin Microbiol
. 2015 May;
53(7):2203-14.
PMID: 25926495
Hepatitis B virus (HBV) infection results in different clinical presentation due to different levels of immune response. Our study aimed to characterize HBV full-length genome quasispecies (QS) in patients with...