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Yang-Chi-Dung Lin

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Articles 18
Citations 1174
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Recent Articles
1.
Xu J, Cai X, Huang J, Huang H, Wang Y, Ji X, et al.
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076546
Triple-negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive progression and limited treatment options, making early diagnosis and prognosis critical. MicroRNAs (miRNAs) are crucial post-transcriptional regulators...
2.
Xu J, Wan J, Huang H, Chen Y, Huang Y, Huang J, et al.
Nucleic Acids Res . 2024 Nov; 53(D1):D138-D146. PMID: 39578697
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding to the 3'-untranslated regions of target mRNAs, influencing various biological processes at the post-transcriptional level. Identifying miRNA transcription...
3.
Cui S, Yu S, Huang H, Lin Y, Huang Y, Zhang B, et al.
Nucleic Acids Res . 2024 Nov; 53(D1):D147-D156. PMID: 39578692
MicroRNAs (miRNAs) are small non-coding RNAs (18-26 nucleotides) that regulate gene expression by interacting with target mRNAs, affecting various physiological and pathological processes. miRTarBase, a database of experimentally validated miRNA-target...
4.
Li Z, Wan J, Li S, Tang Y, Lin Y, Ni J, et al.
Int J Mol Sci . 2024 Jul; 25(14). PMID: 39062881
Ubiquitination, a post-translational modification, refers to the covalent attachment of ubiquitin molecules to substrates. This modification plays a critical role in diverse cellular processes such as protein degradation. The specificity...
5.
Huang Y, Dong D, Zhang W, Wang R, Lin Y, Zuo H, et al.
Database (Oxford) . 2024 Jul; 2024. PMID: 38994794
In recent years, drug repositioning has emerged as a promising alternative to the time-consuming, expensive and risky process of developing new drugs for diseases. However, the current database for drug...
6.
Xu Y, Zhao J, Huang H, Lin Y, Lee T, Huang H, et al.
Front Nutr . 2024 May; 11:1366435. PMID: 38689935
Breast milk (BM) is a primary biofluid that plays a crucial role in infant development and the regulation of the immune system. As a class of rich biomolecules in BM,...
7.
Zuo H, Huang H, Lin Y, Liu K, Lin T, Wang Y, et al.
Molecules . 2023 Dec; 28(23). PMID: 38067658
Ferroptosis is a form of regulated cell death that is characterized by the accumulation of iron-dependent lipid peroxides. The regulation of ferroptosis involves both non-enzymatic reactions and enzymatic mechanisms. Natural...
8.
Huang Y, Huang H, Chen Y, Lin Y, Yao L, Lin T, et al.
Int J Mol Sci . 2023 Sep; 24(18). PMID: 37762364
Drug-target interactions (DTIs) are considered a crucial component of drug design and drug discovery. To date, many computational methods were developed for drug-target interactions, but they are insufficiently informative for...
9.
Li J, Huang Y, Xu J, Zuo H, Tang Y, Huang H, et al.
J Ethnopharmacol . 2023 Sep; 319(Pt 3):117232. PMID: 37757992
Ethnopharmacological Relevance: Sophorae Flavescentis Radix (Kushen) is the primary herb component of Compound Kushen Injection (CKI), an approved clinical treatment for tumors. Despite CKI's widespread use, the underlying mechanisms of...
10.
Tang Y, Chen Y, Huang H, Li S, Zuo H, Chen J, et al.
Chin Med . 2023 Jun; 18(1):74. PMID: 37337262
Background: Herbal medicine Sanqi (SQ), the dried root or stem of Panax notoginseng (PNS), has been reported to have anti-diabetic and anti-obesity effects and is usually administered as a decoction...