Yanelys Cabrera Infante
Overview
Explore the profile of Yanelys Cabrera Infante including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
93
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0
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Recent Articles
1.
Boggiano-Ayo T, Palacios-Oliva J, Lozada-Chang S, Relova-Hernandez E, Gomez-Perez J, Oliva G, et al.
Front Bioeng Biotechnol
. 2023 Dec;
11:1287551.
PMID: 38050488
We have developed a single process for producing two key COVID-19 vaccine antigens: SARS-CoV-2 receptor binding domain (RBD) monomer and dimer. These antigens are featured in various COVID-19 vaccine formats,...
2.
Rojas G, Relova-Hernandez E, Perez-Riveron A, Castro-Martinez C, Diaz-Bravo O, Cabrera Infante Y, et al.
Commun Biol
. 2023 Aug;
6(1):828.
PMID: 37558752
Interleukin-2 (IL-2) engineered versions, with biased immunological functions, have emerged from yeast display and rational design. Here we reshaped the human IL-2 interface with the IL-2 receptor beta chain through...
3.
Perez-Martinez D, Cabrera Infante Y, Sanchez Ramirez B, Rojas G
Sci Rep
. 2022 Jul;
12(1):12268.
PMID: 35851313
HER-1 and HER-2 are tumor-associated antigens overexpressed in several epithelial tumors, and successfully targeted by therapeutic approaches against cancer. Vaccination with their recombinant extracellular domains has had encouraging results in...
4.
Valdes-Balbin Y, Santana-Mederos D, Quintero L, Fernandez S, Rodriguez L, Sanchez Ramirez B, et al.
ACS Chem Biol
. 2021 Jul;
16(7):1223-1233.
PMID: 34219448
Controlling the global COVID-19 pandemic depends, among other measures, on developing preventive vaccines at an unprecedented pace. Vaccines approved for use and those in development intend to elicit neutralizing antibodies...
5.
Rojas G, Tundidor Y, Cabrera Infante Y
MAbs
. 2014 Dec;
6(6):1368-76.
PMID: 25484050
Antibody engineering must be accompanied by mapping strategies focused on identifying the epitope recognized by each antibody to define its unique functional identity. High throughput fine specificity determination remains technically...
6.
Tundidor Y, Garcia-Hernandez C, Pupo A, Cabrera Infante Y, Rojas G
MAbs
. 2014 Apr;
6(4):1013-25.
PMID: 24759767
Molecular details of epidermal growth factor receptor (EGFR) targeting by nimotuzumab, a therapeutic anti-cancer antibody, have been largely unknown. The current study delineated a functional map of their interface, based...
7.
Cabrera Infante Y, Pupo A, Rojas G
MAbs
. 2014 Mar;
6(3):637-48.
PMID: 24589624
Although multiple different procedures to characterize the epitopes recognized by antibodies have been developed, site-directed mutagenesis remains the method of choice to define the energetic contribution of antigen residues to...
8.
Rojas G, Cabrera Infante Y, Pupo A, Carmenate T
MAbs
. 2013 Nov;
6(1):273-85.
PMID: 24253188
The functional dichotomy of antibodies against interleukin-2 (IL-2) is thought to depend upon recognition of different cytokine epitopes. Beyond functional studies, the only molecular evidence obtained so far located the...