Yan Cherel
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Explore the profile of Yan Cherel including associated specialties, affiliations and a list of published articles.
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51
Citations
1622
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Recent Articles
1.
Gernoux G, Guilbaud M, Devaux M, Journou M, Pichard V, Jaulin N, et al.
Mol Ther Methods Clin Dev
. 2021 Mar;
20:660-674.
PMID: 33718516
Adeno-associated virus (AAV) vectors are considered efficient vectors for gene transfer, as illustrated by recent successful clinical trials targeting retinal or neurodegenerative disorders. However, limitations as host immune responses to...
2.
Gait characterization in golden retriever muscular dystrophy dogs using linear discriminant analysis
Fraysse B, Barthelemy I, Qannari E, Rouger K, Thorin C, Blot S, et al.
BMC Musculoskelet Disord
. 2017 Apr;
18(1):153.
PMID: 28403854
Background: Accelerometric analysis of gait abnormalities in golden retriever muscular dystrophy (GRMD) dogs is of limited sensitivity, and produces highly complex data. The use of discriminant analysis may enable simpler...
3.
Toromanoff A, Cherel Y, Guilbaud M, Penaud-Budloo M, Snyder R, Haskins M, et al.
Mol Ther
. 2017 Feb;
16(7):1291-1299.
PMID: 28178483
We developed a drug-free regional intravenous (RI) delivery protocol of recombinant adeno-associated virus (rAAV) 1 and 8 to an entire limb in the nonhuman primate (NHP), and compared the results...
4.
Moreau A, Vandamme C, Segovia M, Devaux M, Guilbaud M, Tilly G, et al.
Mol Ther Methods Clin Dev
. 2015 May;
1:14028.
PMID: 26015970
Preventing untoward immune responses against a specific antigen is a major challenge in different clinical settings such as gene therapy, transplantation, or autoimmunity. Following intramuscular delivery of recombinant adeno-associated virus...
5.
Robriquet F, Lardenois A, Babarit C, Larcher T, Dubreil L, Leroux I, et al.
PLoS One
. 2015 May;
10(5):e0123336.
PMID: 25955839
Background: Several adult stem cell populations exhibit myogenic regenerative potential, thus representing attractive candidates for therapeutic approaches of neuromuscular diseases such as Duchenne Muscular Dystrophy (DMD). We have recently shown...
6.
Larcher T, Lafoux A, Tesson L, Remy S, Thepenier V, Francois V, et al.
PLoS One
. 2014 Oct;
9(10):e110371.
PMID: 25310701
A few animal models of Duchenne muscular dystrophy (DMD) are available, large ones such as pigs or dogs being expensive and difficult to handle. Mdx (X-linked muscular dystrophy) mice only...
7.
Le Guiner C, Stieger K, Toromanoff A, Guilbaud M, Mendes-Madeira A, Devaux M, et al.
PLoS One
. 2014 Sep;
9(9):e102538.
PMID: 25248159
Numerous studies have demonstrated the efficacy of the Adeno-Associated Virus (AAV)-based gene delivery platform in vivo. The control of transgene expression in many protocols is highly desirable for therapeutic applications...
8.
Le Guiner C, Montus M, Servais L, Cherel Y, Francois V, Thibaud J, et al.
Mol Ther
. 2014 Sep;
22(11):1923-35.
PMID: 25200009
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disorder caused by mutations in the dystrophin gene, without curative treatment yet available. Our study provides, for the first time, the overall...
9.
Vabres B, Le Bas-Bernardet S, Riochet D, Cherel Y, Minault D, Hervouet J, et al.
Xenotransplantation
. 2014 Jul;
21(5):431-43.
PMID: 25040113
Background: Human corneal allografting is an established procedure to cure corneal blindness. However, a shortage of human donor corneas as well as compounding economic, cultural, and organizational reasons in many...
10.
Cubizolle A, Serratrice N, Skander N, Colle M, Ibanes S, Gennetier A, et al.
Mol Ther
. 2013 Dec;
22(4):762-73.
PMID: 24343103
Severe deficiency in lysosomal β-glucuronidase (β-glu) enzymatic activity results in mucopolysaccharidosis (MPS) VII, an orphan disease with symptoms often appearing in early childhood. Symptoms are variable, but many patients have...