Yan-E Du
Overview
Explore the profile of Yan-E Du including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
402
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Recent Articles
1.
Yang L, Du Y, Liao F, Huang T, Liu Y, Liu J, et al.
Biomed Pharmacother
. 2024 Mar;
174:116486.
PMID: 38520865
Recurrence and metastasis of gastric cancer is a major therapeutic challenge for treatment. The presence of cancer stem cells (CSCs) is a major obstacle to the success of current cancer...
2.
Qiu Y, Wang X, Sun Y, Du Y, Yin G, Luo H, et al.
Biochim Biophys Acta Mol Basis Dis
. 2023 May;
1869(6):166727.
PMID: 37137433
Cancer-associated fibroblasts (CAFs) are the predominant stromal cells in the microenvironment and play important roles in tumor progression, including chemoresistance. However, the response of CAFs to chemotherapeutics and their effects...
3.
Yang L, Hou Y, Du Y, Li Q, Zhou F, Li Y, et al.
Cell Death Differ
. 2021 Apr;
28(9):2708-2727.
PMID: 33875796
The aberrant classical miRNAs are considered to play significant roles in tumor progression. However, it remains unclear for nonclassical miRNAs, a set of Drosha-independent miRNAs in the process of various...
4.
Zhao M, Hou Y, Du Y, Yang L, Qin Y, Peng M, et al.
Cancer Lett
. 2020 Mar;
478:8-21.
PMID: 32142918
Drosha-dependent canonical microRNAs (miRNAs) play a crucial role in the biological functions and development of cancer. However, the effects of Drosha-independent non-canonical miRNAs remain poorly understood. In our previous work,...
5.
Du Y, Tu G, Yang G, Li G, Yang D, Lang L, et al.
Theranostics
. 2017 Nov;
7(16):3972-3988.
PMID: 29109792
Tumor microenvironment contributes to tumor angiogenesis. However, the role of the activated cancer associated-fibroblasts (CAFs) in angiogenesis is still unclear. Here we report that miR-205/YAP1 signaling in the activated stromal...
6.
Xu L, Hou Y, Tu G, Chen Y, Du Y, Zhang H, et al.
Cell Death Dis
. 2017 Mar;
8(3):e2642.
PMID: 28252644
Drosha is an RNA III-like enzyme that has an aberrant expression in some tumors. Our previous studies showed the aberrant Drosha in gastric tumors. However, the roles of nuclear Drosha,...
7.
Zhang H, Hou Y, Xu L, Zeng Z, Wen S, Du Y, et al.
Dig Dis Sci
. 2015 Dec;
61(4):1080-90.
PMID: 26694172
Background: The nuclear localization of Drosha is critical for its function as a microRNA maturation regulator. Dephosphorylation of Drosha at serine 300 and serine 302 disrupts its nuclear localization, and...
8.
Yang J, Hou Y, Zhou M, Wen S, Zhou J, Xu L, et al.
Int J Biochem Cell Biol
. 2015 Dec;
71:62-71.
PMID: 26693891
Twist, a highly conserved basic Helix-Loop-Helix transcription factor, functions as a major regulator of epithelial-mesenchymal transition (EMT) and tumor metastasis. In different cell models, signaling pathways such as TGF-β, MAPK/ERK,...
9.
Zhou M, Hou Y, Yang G, Zhang H, Tu G, Du Y, et al.
Stem Cells
. 2015 Sep;
34(1):55-66.
PMID: 26418365
Cancer stem cells (CSCs) are a subpopulation of neoplastic cells with self-renewal capacity and limitless proliferative potential as well as high invasion and migration capacity. These cells are commonly associated...
10.
Yang L, Hou Y, Yuan J, Tang S, Zhang H, Zhu Q, et al.
Oncotarget
. 2015 Sep;
6(28):25755-69.
PMID: 26342198
Twist, a key regulator of epithelial-mesenchymal transition (EMT), plays an important role in the development of a tumorigenic phenotype. Energy metabolism reprogramming (EMR), a newly discovered hallmark of cancer cells,...