Yaiza Fernandez-Garcia
Overview
Explore the profile of Yaiza Fernandez-Garcia including associated specialties, affiliations and a list of published articles.
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5
Citations
183
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Recent Articles
1.
Miglioli F, Joel S, Tegoni M, Neira-Pelen P, Gunther S, Carcelli M, et al.
Eur J Med Chem
. 2024 May;
272:116467.
PMID: 38735150
The World Health Organization (WHO) identifies several bunyaviruses as significant threats to global public health security. Developing effective therapies against these viruses is crucial to combat future outbreaks and mitigate...
2.
Gunther S, Reinke P, Fernandez-Garcia Y, Lieske J, Lane T, Ginn H, et al.
Science
. 2021 Apr;
372(6542):642-646.
PMID: 33811162
The coronavirus disease (COVID-19) caused by SARS-CoV-2 is creating tremendous human suffering. To date, no effective drug is available to directly treat the disease. In a search for a drug...
3.
Fernandez-Garcia Y, Ter Horst S, Bassetto M, Brancale A, Neyts J, Rogolino D, et al.
Antiviral Res
. 2020 Sep;
183:104947.
PMID: 32980445
Several fatal bunyavirus infections lack specific treatment. Here, we show that diketo acids engage a panel of bunyavirus cap-snatching endonucleases, inhibit their catalytic activity and reduce viral replication of a...
4.
Ter Horst S, Fernandez-Garcia Y, Bassetto M, Gunther S, Brancale A, Neyts J, et al.
J Antimicrob Chemother
. 2020 Aug;
75(11):3189-3193.
PMID: 32766680
Objectives: Baloxavir acid is an endonuclease inhibitor approved for use against influenza. We evaluated whether this compound also targets the endonuclease domain of orthobunyaviruses and therefore could potentially be used...
5.
Fernandez-Garcia Y, Reguera J, Busch C, Witte G, Sanchez-Ramos O, Betzel C, et al.
PLoS Pathog
. 2016 Jun;
12(6):e1005635.
PMID: 27300328
Andes virus (ANDV) is a human-pathogenic hantavirus. Hantaviruses presumably initiate their mRNA synthesis by using cap structures derived from host cell mRNAs, a mechanism called cap-snatching. A signature for a...