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Yabing Nan

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Articles 12
Citations 137
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Recent Articles
1.
He X, Wang Q, Cheng X, Wang W, Li Y, Nan Y, et al.
Cell . 2025 Mar; PMID: 40023152
Vitamin C (vitC) is essential for health and shows promise in treating diseases like cancer, yet its mechanisms remain elusive. Here, we report that vitC directly modifies lysine residues to...
2.
Nan Y, Wu X, Luo Q, Chang W, Zhao P, Zhang L, et al.
Proc Natl Acad Sci U S A . 2024 May; 121(19):e2315348121. PMID: 38701117
Ovarian cancer is an aggressive gynecological tumor characterized by a high relapse rate and chemoresistance. Ovarian cancer exhibits the cancer hallmark of elevated glycolysis, yet effective strategies targeting cancer cell...
3.
Yu X, Zhao P, Luo Q, Wu X, Wang Y, Nan Y, et al.
Oncogene . 2023 Dec; 43(6):420-433. PMID: 38092960
Dysregulated expression of long-stranded non-coding RNAs is strongly associated with carcinogenesis. However, the precise mechanisms underlying their involvement in ovarian cancer pathogenesis remain poorly defined. Here, we found that lncRNA...
4.
Nan Y, Liu S, Luo Q, Wu X, Zhao P, Chang W, et al.
Cell Rep . 2023 Oct; 42(10):113273. PMID: 37858471
RNA N-methyladenosine (mA) modification is implicated in cancer progression, yet its role in regulating long noncoding RNAs during cancer progression remains unclear. Here, we report that the mA demethylase fat...
5.
Zhao P, Wang Y, Yu X, Nan Y, Liu S, Li B, et al.
Front Med . 2023 Jul; 17(5):924-938. PMID: 37434064
Long noncoding RNAs (lncRNAs) play a crucial regulatory role in the development and progression of multiple cancers. However, the potential mechanism by which lncRNAs affect the recurrence and metastasis of...
6.
Chang W, Luo Q, Wu X, Nan Y, Zhao P, Zhang L, et al.
Cell Rep . 2022 Oct; 41(4):111561. PMID: 36288705
Oral and esophageal squamous cell carcinomas (SCCs) are associated with high mortality, yet the molecular mechanisms underlying these malignancies are largely unclear. We show that DNA hypermethylation of otubain 2...
7.
Nan Y, Luo Q, Wu X, Chang W, Zhao P, Liu S, et al.
Mol Ther . 2022 Oct; 31(2):552-568. PMID: 36245126
Inducing cancer cell apoptosis through cytotoxic reagents is the main therapeutic strategy for diverse cancer types. However, several antiapoptotic factors impede curative cancer therapy by driving cancer cells to resist...
8.
Nan Y, Luo Q, Wu X, Liu S, Zhao P, Chang W, et al.
Cancer Res . 2022 Jun; 82(16):2887-2903. PMID: 35731019
Significance: This study identifies D-AS2 as a targetable lipid-related long noncoding RNA that increases phospholipase D activity to promote YAP signaling, triggering chemoresistance in SCC.
9.
Luo Q, Wu X, Zhao P, Nan Y, Chang W, Zhu X, et al.
Adv Sci (Weinh) . 2021 Apr; 8(8):2002874. PMID: 33898171
Apoptosis-inducing factor (AIF) plays a dual role in regulating cell survival and apoptosis, acting as a prosurvival factor in mitochondria via its NADH oxidoreductase activity and activating the caspase-independent apoptotic...
10.
Luo Q, Wu X, Chang W, Zhao P, Zhu X, Chen H, et al.
Cancer Res . 2020 Oct; 80(19):4302. PMID: 33008806
No abstract available.