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Ya-Yu Chiang

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Articles 9
Citations 127
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Recent Articles
1.
Chang Y, Chen Y, Chen P, Chen Y, Maqbool F, Ho T, et al.
ACS Appl Mater Interfaces . 2023 Feb; 15(9):12473-12484. PMID: 36732679
Two-phase flow separation is a key step in various downstream purification processes. The use of a separator with controllable flow behavior is recommended to avoid contamination. In this study, a...
2.
Tu K, Yu L, Sie Z, Hsu H, Al-Jamal K, Wang J, et al.
Micromachines (Basel) . 2021 Jan; 12(1). PMID: 33396953
Three-dimensional (3D) cell cultures and organs-on-a-chip have been developed to construct microenvironments that resemble the environment within the human body and to provide a platform that enables clear observation and...
3.
Chen T, Huang C, Xie Y, Chiang Y, Chen Y, Hsueh H
ACS Appl Mater Interfaces . 2019 Oct; 11(43):40875-40885. PMID: 31588736
Inspired by complex multifunctional leaves, in this study, we created robust hierarchically wrinkled nanoporous polytetrafluoroethene (PTFE) surfaces that exhibit superhydrophobic properties by combination of PTFE micellization and spontaneous surface wrinkling...
4.
Dinh N, Chiang Y, Hardelauf H, Waide S, Janasek D, West J
J Vis Exp . 2014 Jun; (87). PMID: 24894871
Microfluidic embodiments of the Campenot chamber have attracted great interest from the neuroscience community. These interconnected co-culture platforms can be used to investigate a variety of questions, spanning developmental and...
5.
Chiang Y, Haeri S, Gizewski C, Stewart J, Ehrhard P, Shrimpton J, et al.
Anal Chem . 2013 Dec; 85(23):11560-7. PMID: 24295019
This paper describes a microfluidic quenched flow platform for the investigation of ligand-mediated cell surface processes with unprecedented temporal resolution. A roll-slip behavior caused by cell-wall-fluid coupling was documented and...
6.
Dinh N, Chiang Y, Hardelauf H, Baumann J, Jackson E, Waide S, et al.
Lab Chip . 2013 Feb; 13(7):1402-12. PMID: 23403713
In this paper we present compartmentalized neuron arraying (CNA) microfluidic circuits for the preparation of neuronal networks using minimal cellular inputs (10-100-fold less than existing systems). The approach combines the...
7.
Chiang Y, West J
Lab Chip . 2013 Feb; 13(6):1031-4. PMID: 23385220
A pinched-flow deflection technology was developed for rapid single cell switching between biochemical microenvironments. Millisecond switching was used to stimulate and preserve epidermal growth factor receptor (EGFR) autophosphorylation transitions. Intramolecular...
8.
Hardelauf H, Frimat J, Stewart J, Schormann W, Chiang Y, Lampen P, et al.
Lab Chip . 2010 Nov; 11(3):419-28. PMID: 21079873
We report the use of thin film poly(dimethylsiloxane) (PDMS) prints for the arrayed mass production of highly uniform 3-D human HT29 colon carcinoma spheroids. The spheroids have an organotypic density...
9.
Frimat J, Becker M, Chiang Y, Marggraf U, Janasek D, Hengstler J, et al.
Lab Chip . 2010 Oct; 11(2):231-7. PMID: 20978708
We present a highly parallel microfluidic approach for contacting single cell pairs. The approach combines a differential fluidic resistance trapping method with a novel cellular valving principle for homotypic and...