Y V Mukhin
Overview
Explore the profile of Y V Mukhin including associated specialties, affiliations and a list of published articles.
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13
Citations
444
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Recent Articles
1.
Raymond J, Mukhin Y, Gelasco A, Turner J, Collinsworth G, Gettys T, et al.
Pharmacol Ther
. 2002 Mar;
92(2-3):179-212.
PMID: 11916537
The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into 7 subfamilies by convention, 6 of which include 13 different genes for G-protein-coupled receptors. Those subfamilies have been characterized by overlapping...
2.
Heise C, Santos W, Schreihofer A, Heasley B, Mukhin Y, Macdonald T, et al.
Mol Pharmacol
. 2001 Nov;
60(6):1173-80.
PMID: 11723223
The physiological implications of lysophosphatidic acid occupancy of individual receptors are largely unknown because selective agonists/antagonists are unavailable currently. The molecular cloning of three high-affinity lysophosphatidic acid receptors, LPA1, LPA2,...
3.
Haastrup A, Gadegbeku C, Zhang D, Mukhin Y, Greene E, Jaffa A, et al.
Hypertension
. 2001 Oct;
38(4):858-63.
PMID: 11641299
Obese hypertensives have increased nonesterified fatty acids (NEFAs) and alpha-adrenergic vascular reactivity. Raising NEFAs locally with intralipid and heparin augments dorsal hand venoconstrictor responses to phenylephrine, an alpha(1)-adrenoceptor agonist. The...
4.
WEBB J, Yates P, Yang Q, Mukhin Y, Lanier S
Am J Physiol Heart Circ Physiol
. 2001 Sep;
281(4):H1545-52.
PMID: 11557542
Adenylyl cyclases present a potential focal point for signal integration in vascular smooth muscle cells (VSMC) influencing contractile state and cellular responses to vessel wall injury. In the present study,...
5.
Mukhin Y, Vlasova T, Jaffa A, Collinsworth G, Bell J, Tholanikunnel B, et al.
J Biol Chem
. 2001 Mar;
276(20):17339-46.
PMID: 11278760
We used a cultured murine cell model of the inner medullary collecting duct (mIMCD-3 cells) to examine the regulation of the ubiquitous sodium-proton exchanger, Na+/H+ exchanger isoform 1 (NHE-1), by...
6.
Chen R, Mukhin Y, Garnovskaya M, Thielen T, Iijima Y, Huang C, et al.
Am J Physiol Renal Physiol
. 2000 Sep;
279(3):F440-8.
PMID: 10966923
We constructed an expression vector for a fusion protein [ANG II type 1a receptor-green fluorescent protein (AT(1a)R-GFP)] consisting of enhanced GFP attached to the COOH terminus of the rat AT(1a)R....
7.
Gooz M, Hammond C, Larsen K, Mukhin Y, Smolka A
Am J Physiol Gastrointest Liver Physiol
. 2000 Jun;
278(6):G981-91.
PMID: 10859229
Clinical studies and in vitro data from isolated parietal cells suggest that acute Helicobacter pylori infection inhibits acid secretion. Gastric acidification is mediated by H(+)-K(+)-ATPase, an integral protein of parietal...
8.
Dorman B, New R, Bond B, Mukherjee R, Mukhin Y, McElmurray J, et al.
Anesth Analg
. 2000 Apr;
90(5):1080-5.
PMID: 10781456
Transient left ventricular (LV) dysfunction can occur after cardioplegic arrest. The contributory mechanisms for this phenomenon are not completely understood. We tested the hypothesis that exposure of LV myocytes to...
9.
Mukhin Y, Garnovskaya M, Collinsworth G, Grewal J, Pendergrass D, Nagai T, et al.
Biochem J
. 2000 Mar;
347 Pt 1:61-7.
PMID: 10727402
The hypothesis of this work is that the 'serotonin' or 5-hydroxytryptamine (5-HT)(1A) receptor, which activates the extracellular signal-regulated kinase (ERK) through a G(i)betagamma-mediated pathway, does so through the intermediate actions...
10.
Wu G, Bogatkevich G, Mukhin Y, Benovic J, Hildebrandt J, Lanier S
J Biol Chem
. 2000 Mar;
275(12):9026-34.
PMID: 10722752
Gbetagamma binds directly to the third intracellular (i3) loop subdomain of the M(3)-muscarinic receptor (MR). In this report, we identified the Gbetagamma binding motif and G-protein-coupled receptor kinase (GRK2) phosphorylation...