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Y Michotte

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Articles 114
Citations 892
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Recent Articles
1.
Van Eeckhaut A, Vanfleteren P, Van Schoors J, Van Wanseele Y, Poelaert J, Michotte Y
J Clin Pharm Ther . 2017 Mar; 42(3):306-310. PMID: 28295465
What Is Known And Objective: In our university hospital (UZBrussel), one of the options to control post-operative pain after a Caesarean section under general anaesthesia is to administer piritramide by...
2.
Loyens E, Vermoesen K, Schallier A, Michotte Y, Smolders I
Brain Res . 2012 Jan; 1436:43-50. PMID: 22208648
The possible involvement of oxytocin (OT) in the generation of seizures has not received a lot of attention in the past, although generalized epileptic convulsions were observed in humans following...
3.
Caljon G, Caveliers V, Lahoutte T, Stijlemans B, Ghassabeh G, Van Den Abbeele J, et al.
Br J Pharmacol . 2011 Oct; 165(7):2341-53. PMID: 22013955
Background And Purpose: Nanobodies are promising antigen-binding moieties for molecular imaging and therapeutic purposes because of their favourable pharmacological and pharmacokinetic properties. However, the capability of monovalent nanobodies to reach...
4.
Pravda M, Bogaert L, Sarre S, Ebinger G, Kauffmann J, Michotte Y
Anal Chem . 2011 Jun; 69(13):2354-61. PMID: 21639368
The continuous on-line monitoring of endogenous quinones has been realized for the first time in an animal model of brain ischemia induced by a vasoconstrictor peptide, endothelin-1. A microdialysis probe,...
5.
Loyens E, Schallier A, Chai S, De Bundel D, Vanderheyden P, Michotte Y, et al.
Seizure . 2011 May; 20(8):602-5. PMID: 21612947
The peptide angiotensin IV (Ang IV) influences seizure susceptibility in rat and mouse models. Indeed, Ang IV has been shown to protect rats from limbic seizures in the focal pilocarpine...
6.
Mertens B, Massie A, Michotte Y, Sarre S
Neuroscience . 2009 Apr; 162(1):148-54. PMID: 19383530
Several types of brain injuries have been associated with alterations in the striatal expression of neurotrophic factors, including glial cell line-derived neurotrophic factor (GDNF). However, contradictory results on the striatal...
7.
Umbrain V, Lauwers M, Shi L, Smolders I, Michotte Y, Poelaert J
Br J Anaesth . 2009 Mar; 102(4):540-5. PMID: 19252201
Background: Bupivacaine has a lower incidence of transient neurological symptoms than lidocaine after intrathecal (i.t.) injection. The increased toxic potential of lidocaine does not support its use in the clinical...
8.
Clinckers R, Smolders I, Michotte Y, Ebinger G, Danhof M, Voskuyl R, et al.
Br J Pharmacol . 2008 Oct; 155(7):1127-38. PMID: 18836479
Background And Purpose: Accurate prediction of biophase pharmacokinetics (PK) is essential to optimize pharmacotherapy in epilepsy. Here, we characterized the PK of the active metabolite of oxcarbazepine, 10,11-dihydro-10-hydroxy-carbamazepine (MHD) in...
9.
Umbrain V, Shi L, Lauwers M, Smolders I, Michotte Y, Camu F
Br J Anaesth . 2008 Aug; 101(5):716-22. PMID: 18716004
Background: In this study, we have investigated whether intrathecal (i.t.) lidocaine administration is accompanied with changes of cerebrospinal fluid (CSF) prostaglandin E(2) (PGE(2)) levels. Methods: Rats were anaesthetized for i.t....
10.
Demaegdt H, Smitz L, De Backer J, Le M, Bauwens M, Szemenyei E, et al.
Br J Pharmacol . 2008 Jun; 154(4):872-81. PMID: 18536739
Background And Purpose: Insulin-regulated aminopeptidase (IRAP) and the insulin-dependent glucose transporter GLUT4 colocalize in specific intracellular vesicles (that is, GLUT4 vesicles). These vesicles move slowly to the cell surface, but...