Y Lachance
Overview
Explore the profile of Y Lachance including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
258
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0
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Recent Articles
1.
Blais A, Labrie Y, Pouliot F, Lachance Y, Labrie C
Biochem Biophys Res Commun
. 1998 Jun;
247(1):146-53.
PMID: 9636670
The cyclin-dependent kinase (CDK) inhibitor p18 blocks progression of the cell cycle by associating with the cyclin D-dependent kinases CDK6 and CDK4. To better understand the regulation of p18 gene...
2.
Lapointe J, Lachance Y, Labrie Y, Labrie C
Cancer Res
. 1996 Oct;
56(20):4586-9.
PMID: 8840966
Progression from G1 to the S-phase of the cell cycle is controlled by a family of low molecular weight cyclin-dependent kinase (CDK) inhibitors. The importance of these proteins in cell...
3.
Labrie Y, Durocher F, Lachance Y, Turgeon C, Simard J, Labrie C, et al.
DNA Cell Biol
. 1995 Oct;
14(10):849-61.
PMID: 7546291
The isozymes of the 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) gene family are responsible for the formation of the 17 beta-hydroxysteroids delta 5-androstene-3 beta,17 beta-diol, testosterone, 17 beta-estradiol, and dihydrotestosterone from...
4.
Labrie F, Sugimoto Y, Luu-The V, Simard J, Lachance Y, Bachvarov D, et al.
Endocrinology
. 1992 Sep;
131(3):1571-3.
PMID: 1505484
The best known activity of steroid 5 alpha-reductase is the transformation of testosterone into dihydrotestosterone, the most potent androgen. Two types of human steroid 5 alpha-reductase cDNAs and the type...
5.
Labrie F, Simard J, Luu-The V, Pelletier G, Belanger A, Lachance Y, et al.
J Steroid Biochem Mol Biol
. 1992 Mar;
41(3-8):421-35.
PMID: 1562516
The enzyme 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase (3 beta-HSD) catalyzes the oxidation and isomerization of 5-ene-3 beta-hydroxypregnene and 5-ene-hydroxyandrostene steroid precursors into the corresponding 4-ene-ketosteroids necessary for the formation of all...
6.
Lachance Y, Luu-The V, Labrie C, Simard J, Dumont M, de Launoit Y, et al.
J Biol Chem
. 1992 Feb;
267(5):3551.
PMID: 1737804
No abstract available.
7.
Lachance Y, Luu-The V, Verreault H, Dumont M, Rheaume E, Leblanc G, et al.
DNA Cell Biol
. 1991 Dec;
10(10):701-11.
PMID: 1741954
While classical 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase deficiency (3 beta-HSD) is a known cause of adrenal hyperplasia resulting in ambiguous genitalia and adrenal insufficiency at birth, nonclassical or late-onset...
8.
Rheaume E, LeBlanc J, Lachance Y, Labrie F, Simard J
Hum Genet
. 1991 Oct;
87(6):753-4.
PMID: 1682237
Analysis of amplified polymerase chain reaction products of 575 bp from the fourth exon of the human type I 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase gene at locus HSD beta...
9.
Luu-The V, Takahashi M, de Launoit Y, Dumont M, Lachance Y, Labrie F
Biochemistry
. 1991 Sep;
30(36):8861-5.
PMID: 1832298
Complementary DNA encoding human 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase (3 beta-HSD) has been expressed in transfected GH4C1 with use of the cytomegalovirus promoter. The activity of the expressed protein clearly shows...
10.
Rheaume E, Lachance Y, Zhao H, Breton N, Dumont M, de Launoit Y, et al.
Mol Endocrinol
. 1991 Aug;
5(8):1147-57.
PMID: 1944309
The 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta HSD) enzyme catalyzes the oxidation and isomerization of delta 5-3 beta-hydroxysteroid precursors into delta 4-ketosteroids, thus leading to the formation of...