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Y F M Ramos

Explore the profile of Y F M Ramos including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 86
Followers 0
Related Specialties
Rheumatology
Orthopedics
Endocrinology
Top 10 Co-Authors
I Meulenbelt
R G H H Nelissen
E Houtman
P E Slagboom
R Coutinho de Almeida
W den Hollander
M Tuerlings
I Boone
N Bomer
H E D Suchiman
Published In
Osteoarthritis Cartilage
Ann Rheum Dis
Arthritis Res Ther
Eur J Endocrinol
Affiliations
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Recent Articles
1.
Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model
Korthagen N, Houtman E, Boone I, Coutinho de Almeida R, Sivasubramaniyan K, Mahdad R, et al.
Arthritis Res Ther . 2024 Apr; 26(1):91. PMID: 38664820
Objective: To characterize aspects of triiodothyronine (T3) induced chondrocyte terminal maturation within the molecular osteoarthritis pathophysiology using the previously established T3 human ex vivo osteochondral explant model. Designs: RNA-sequencing was...
2.
WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes
Tuerlings M, Janssen G, Boone I, van Hoolwerff M, Rodriguez Ruiz A, Houtman E, et al.
Osteoarthritis Cartilage . 2022 Oct; 31(1):39-48. PMID: 36208715
Objective: To explore the co-expression network of the osteoarthritis (OA) risk gene WWP2 in articular cartilage and study cartilage characteristics when mimicking the effect of OA risk allele rs1052429-A on...
3.
Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin
Houtman E, Coutinho de Almeida R, Tuerlings M, Suchiman H, Broekhuis D, Nelissen R, et al.
Osteoarthritis Cartilage . 2021 May; 29(8):1193-1202. PMID: 33984465
Objective: We here aimed to characterize changes of Matrix Gla Protein (MGP) expression in relation to its recently identified OA risk allele rs1800801-T in OA cartilage, subchondral bone and human...
4.
Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis
Pelsma I, Claessen K, Slagboom P, Van Heemst D, Pereira A, Kroon H, et al.
Eur J Endocrinol . 2020 Oct; 184(1):29-39. PMID: 33112260
Introduction: Pathologically high growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels in patients with acromegaly are associated with arthropathy. Several studies highlight the potential role of the GH/IGF-1 axis...
5.
Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells
Bomer N, den Hollander W, Suchiman H, Houtman E, Slieker R, Heijmans B, et al.
Osteoarthritis Cartilage . 2016 Mar; 24(8):1423-30. PMID: 26995110
Objectives: To compare the epigenetic landscape of 3D cell models of human primary articular chondrocytes (hPACs) and human bone-marrow derived mesenchymal stem cells (hBMSCs) and their respective autologous articular cartilage....
6.
Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches
den Hollander W, Ramos Y, Bos S, Bomer N, van der Breggen R, Lakenberg N, et al.
Ann Rheum Dis . 2014 Sep; 73(12):2208-12. PMID: 25261579
Objectives: To elucidate the functional epigenomic landscape of articular cartilage in osteoarthritis (OA) affected knee and hip joints in relation to gene expression. Methods: Using Illumina Infinium HumanMethylation450 BeadChip arrays,...