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Xuyu Zhou

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Articles 69
Citations 2896
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Recent Articles
1.
Wei X, Zhang J, Cui J, Xu W, Zhao G, Guo C, et al.
Theranostics . 2024 May; 14(7):2897-2914. PMID: 38773985
IL-35 potently inhibits immune responses both and . However, the specific characteristics of IL-35-producing cells, including their developmental origin, cellular phenotype, and function, are unknown. By using a novel IL-35...
2.
Wang T, Guo J, Li L, Jin Q, Zhang F, Hou B, et al.
Cell Rep . 2024 May; 43(5):114222. PMID: 38735046
The activation and specialization of regulatory T cells (Tregs) are crucial for maintaining immune self-tolerance; however, the regulation of these processes by histone modifications is not fully understood. Here, we...
3.
Zhang M, Xu W, Luo L, Guan F, Wang X, Zhu P, et al.
Commun Biol . 2024 Apr; 7(1):512. PMID: 38684865
Neoantigens derived from somatic mutations in Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS), the most frequently mutated oncogene, represent promising targets for cancer immunotherapy. Recent research highlights the potential role...
4.
Zhu X, Hong S, Bu J, Liu Y, Liu C, Li R, et al.
Sci Adv . 2024 Mar; 10(13):eadk0858. PMID: 38552009
The long-lasting humoral immunity induced by viral infections or vaccinations depends on memory B cells with greatly increased affinity to viral antigens, which are evolved from germinal center (GC) responses....
5.
Zhuang Q, Chen S, Zhou X, Jia X, Zhang M, Tan N, et al.
Am J Gastroenterol . 2024 Feb; 119(5):803-813. PMID: 38345252
Introduction: Los Angeles grade C/D esophagitis is a severe manifestation of gastroesophageal reflux disease that require active treatment and close follow-up. Potassium competitive acid blockers (P-CAB) are promising alternatives to...
6.
Lin Y, Wan Z, Liu B, Yao J, Li T, Yang F, et al.
Cell Res . 2024 Feb; 34(4):295-308. PMID: 38326478
Autoreactive B cells are silenced through receptor editing, clonal deletion and anergy induction. Additional autoreactive B cells are ignorant because of physical segregation from their cognate autoantigen. Unexpectedly, we find...
7.
Zhao J, Zhang H, Jiang L, Cheng F, Li W, Wang Z, et al.
Microbiol Spectr . 2024 Feb; 12(3):e0243523. PMID: 38319108
It is urgently needed to evaluate the necessity and benefits of booster vaccination against the coronavirus 2 of the severe acute respiratory syndrome (SARS-CoV-2) Omicron to facilitate clinical decision-making for...
8.
Wang X, Geng S, Meng J, Kang N, Liu X, Xu Y, et al.
J Clin Invest . 2023 Dec; 133(24). PMID: 38099494
The suppression mechanism of Tregs remains an intensely investigated topic. As our focus has shifted toward a model centered on indirect inhibition of DCs, a universally applicable effector mechanism controlled...
9.
Lyu H, Yuan G, Liu X, Wang X, Geng S, Xia T, et al.
Elife . 2023 Dec; 12. PMID: 38055613
Thymus-originated tTregs and in vitro induced iTregs are subsets of regulatory T cells. While they share the capacity of immune suppression, their stabilities are different, with iTregs losing their phenotype...
10.
Gu Q, Zhao X, Guo J, Jin Q, Wang T, Xu W, et al.
Cell Rep . 2023 Jul; 42(8):112877. PMID: 37498744
Foxp3 is the master transcription factor for regulatory T cells (Tregs). Alternative splicing of human Foxp3 results in the expression of two isoforms: the full length and an exon 2-deleted...