Xuyan Peng
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Explore the profile of Xuyan Peng including associated specialties, affiliations and a list of published articles.
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11
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74
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Recent Articles
1.
Liu B, Lang Y, Li Y, Jiang M, Xue M, Jia X, et al.
Exp Eye Res
. 2025 Mar;
254:110316.
PMID: 40023307
Genetic mutations in Hsf4 cause developmental defect of lens at postnatal age. However, the regulatory effect of Hsf4 mutations on retinal homeostasis have not been elucidated. Here we found that...
2.
Jia X, Wang Y, Jiang M, Chen D, Shang G, Liu B, et al.
J Biol Chem
. 2024 Dec;
301(2):108126.
PMID: 39725039
Genetic mutations in retinol dehydrogenase 5 (RDH5), a rate-limiting enzyme of the visual cycle, is associated with nyctalopia, age-related macular disease, and stationary congenital fundus albipunctatus (FA). A majority of...
3.
The generation and characterization of a transgenic zebrafish line with lens-specific Cre expression
Peng X, Jia X, Shang G, Xue M, Jiang M, Chen D, et al.
Mol Vis
. 2024 Apr;
30:123-136.
PMID: 38601019
Purpose: Danio rerio zebrafish constitute a popular model for studying lens development and congenital cataracts. However, the specific deletion of a gene with a Cre/LoxP system in the zebrafish lens...
4.
Liu R, Lu Y, Peng X, Jia J, Ruan Y, Shi S, et al.
Front Endocrinol (Lausanne)
. 2023 Mar;
14:1054665.
PMID: 36864841
Introduction: 1α,25-dihydroxyvitamin D3 (1α,25[OH]VD) is a hormone known for its key roles in calcium absorption and nutrient metabolism. In teleost fishes, 1α,25(OH)VD insufficiency causes impaired glucose metabolism and lipid oxidation....
5.
Chen D, Liu B, Wang Y, Jiang M, Shang G, Xue M, et al.
FASEB J
. 2023 Feb;
37(3):e22832.
PMID: 36826429
The dysfunction of CRALBP, a key regulator of the visual cycle, is associated with retinitis punctata albescens characterized by night vision loss and retinal degeneration. In this paper, we find...
6.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, et al.
Biogerontology
. 2023 Feb;
24(5):813-827.
PMID: 36738354
SARS-Cov-2 infection, which has caused the COVID-19 global pandemic, triggers cellular senescence. In this study, we investigate the role of the SARS-COV-2 spike protein (S-protein) in regulating the senescence of...
7.
Chen D, Peng X, Wang Y, Jiang M, Xue M, Shang G, et al.
Aging (Albany NY)
. 2021 Sep;
13(17):21547-21570.
PMID: 34495872
The senescence of retinal pigment epithelial (RPE) cells is associated with age-related macular degeneration (AMD), a leading cause of blindness in the world. HSP90 is a predominant chaperone that regulates...
8.
Cui X, Du C, Wan S, Wu D, Yan L, Zhang J, et al.
Biochim Biophys Acta Mol Basis Dis
. 2021 Aug;
1867(11):166233.
PMID: 34339841
Genetic mutations in heat shock factor 4 (Hsf4) is associated with both congenital and age-related cataracts. Hsf4 regulates lens development through its ability to both activate and inhibit transcription. Previous...
9.
Shi X, Guan K, Peng X, Xu B, Zhou X, Wang S, et al.
Brain Behav Immun
. 2021 Jan;
94:327-337.
PMID: 33412253
Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent psychiatric disorders in children. The orexigenic hormone ghrelin is important in neuroprotection and neurodevelopment, which may play an important...
10.
Shang G, Peng X, Ji C, Zhai G, Ruan Y, Lou Q, et al.
Biol Reprod
. 2019 Jul;
101(4):760-770.
PMID: 31322169
In recent studies, luteinizing hormone (LH) was reported to play important roles in oocyte maturation. However, the mechanism by which LH signaling, especially regarding the steroidogenesis process, affects oocyte maturation...