Xuehan Zhuang
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Explore the profile of Xuehan Zhuang including associated specialties, affiliations and a list of published articles.
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18
Citations
1058
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Recent Articles
1.
Zhang L, Gao M, Wu Y, Liu H, Zhuang X, Zhou Y, et al.
Med Rev (2021)
. 2024 Dec;
4(6):531-543.
PMID: 39664081
Objectives: Resistance to apoptosis in esophageal squamous cell carcinoma (ESCC) constitutes a significant impediment to treatment efficacy. Exploring alternative cell death pathways and their regulatory factors beyond apoptosis is crucial...
2.
Zhuang X, Ye R, Zhou Y, Cheng M, Cui H, Wang L, et al.
Genome Med
. 2024 Apr;
16(1):50.
PMID: 38566210
Background: Mitochondria play essential roles in tumorigenesis; however, little is known about the contribution of mitochondrial DNA (mtDNA) to esophageal squamous cell carcinoma (ESCC). Whole-genome sequencing (WGS) is by far...
3.
Wang L, Zhou Y, Cui H, Zhuang X, Cheng C, Weng Y, et al.
Cancer Gene Ther
. 2023 Nov;
31(1):131-147.
PMID: 37985722
Tumor-infiltrating B-lineage cells have become predictors of prognosis and immunotherapy responses in various cancers. However, limited knowledge about their infiltration and migration patterns has hindered the understanding of their anti-tumor...
4.
Cui H, Zhou Y, Wang F, Cheng C, Zhang W, Sun R, et al.
Nat Commun
. 2022 Oct;
13(1):6296.
PMID: 36272974
Esophageal squamous cell carcinoma (ESCC) demonstrates high genome instability. Here, we analyze 528 whole genomes to investigate structural variations' mechanisms and biological functions. SVs show multi-mode distributions in size, indicating...
5.
Chau J, Yu M, Chui M, Yeung C, Kwok A, Zhuang X, et al.
NPJ Genom Med
. 2022 Mar;
7(1):23.
PMID: 35314707
Traditional carrier screening has been utilized for the detection of carriers of genetic disorders. Since a comprehensive assessment of the carrier frequencies of recessive conditions in the Southern Chinese population...
6.
Tang C, Mononen M, Lam W, Jin S, Zhuang X, Garcia-Barcelo M, et al.
JCI Insight
. 2021 Dec;
7(2).
PMID: 34905512
Tetralogy of Fallot (TOF) is the most common cyanotic heart defect, yet the underlying genetic mechanisms remain poorly understood. Here, we performed whole-genome sequencing analysis on 146 nonsyndromic TOF parent-offspring...
7.
Zhuang X, Ye R, So M, Lam W, Karim A, Yu M, et al.
NAR Genom Bioinform
. 2021 Feb;
2(3):lqaa071.
PMID: 33575619
Detection of copy number variations (CNVs) is essential for uncovering genetic factors underlying human diseases. However, CNV detection by current methods is prone to error, and precisely identifying CNVs from...
8.
Zhang L, Zhou Y, Cheng C, Cui H, Cheng L, Kong P, et al.
Am J Hum Genet
. 2020 Sep;
107(3):579.
PMID: 32888509
No abstract available.
9.
Zhang L, Zhou Y, Cheng C, Cui H, Cheng L, Kong P, et al.
Am J Hum Genet
. 2020 Aug;
107(2):375.
PMID: 32763191
No abstract available.
10.
Tang C, Li P, Lai F, Fu A, Lau S, So M, et al.
Gastroenterology
. 2018 Sep;
155(6):1908-1922.e5.
PMID: 30217742
Background & Aims: Hirschsprung disease, or congenital aganglionosis, is believed to be oligogenic-that is, caused by multiple genetic factors. We performed whole-genome sequence analyses of patients with Hirschsprung disease to...