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Xuechen Tian

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Articles 22
Citations 150
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Recent Articles
1.
Tian X, Chen L, Zhou J, Wang E, Wang M, Jakubovics N, et al.
BMC Biol . 2024 Oct; 22(1):234. PMID: 39397000
Background: Pangolins are the only mammals that have overlapping scales covering most of their bodies, and they play a crucial role in the ecosystem, biological research, and human health and...
2.
Song L, Yang Y, Tian X
Cancer Drug Resist . 2024 Jun; 7:17. PMID: 38835341
Melanoma still reaches thousands of new diagnoses per year, and its aggressiveness makes recovery challenging, especially for those with stage III/IV unresectable melanoma. Immunotherapy, emerging as a beacon of hope,...
3.
Tian X, Teo W, Yang Y, Dong L, Wong A, Chen L, et al.
BMC Microbiol . 2024 May; 24(1):185. PMID: 38802738
Background: Schaalia species are primarily found among the oral microbiota of humans and other animals. They have been associated with various infections through their involvement in biofilm formation, modulation of...
4.
Deng S, Tian X, Belshaw R, Zhou J, Zhang S, Yang Y, et al.
Sci Rep . 2024 Jan; 14(1):910. PMID: 38195813
Protection of the Critically Endangered East Asian Pangolin species is hampered by the vulnerability of captive individuals to infection. Studies have previously shown the pangolin to have a unique pseudogenisation...
5.
Song K, Chen L, Suo N, Kong X, Li J, Wang T, et al.
PeerJ . 2023 Dec; 11:e16476. PMID: 38084141
Background: is a highly prevalent bacterial species known for its ability to cause various infections and its remarkable adaptability and biofilm-forming capabilities. In earlier work, we conducted research involving the...
6.
Tian X, Teo W, Wee W, Yang Y, Ahmed H, Jakubovics N, et al.
BMC Genomics . 2023 Dec; 24(1):734. PMID: 38049764
Background: Actinomyces strains are commonly found as part of the normal microflora on human tissue surfaces, including the oropharynx, gastrointestinal tract, and female genital tract. Understanding the diversity and characterization...
7.
Wong A, Chi W, Yu J, Bi C, Tian X, Yang Y, et al.
Nat Plants . 2023 Sep; 9(9):1389-1397. PMID: 37709954
In bacteria, fungi and animals, 3'-5'-cyclic adenosine monophosphate (cAMP) and adenylate cyclases (ACs), enzymes that catalyse the formation of 3',5'-cAMP from ATP, are recognized as key signalling components. In contrast,...
8.
Song L, Li C, Yu J, Yang Y, Tian X, Choo S
Sci Rep . 2023 Aug; 13(1):12548. PMID: 37532809
Melanoma is a type of cancer with abnormal proliferation of melanocytes and is one of the most diagnosed cancer types. In traditional Chinese medicine, pangolin scales have been used to...
9.
Dong L, Vargas C, Tian X, Chu X, Yin C, Wong A, et al.
Int J Mol Sci . 2023 Jun; 24(12). PMID: 37373523
Melanoma is a highly malignant skin cancer that is known for its resistance to treatments. In recent years, there has been significant progress in the study of non-apoptotic cell death,...
10.
Qin H, Wei A, Wang Y, Wang L, Xu H, Zhan Y, et al.
Eur J Med Chem . 2023 Apr; 254:115371. PMID: 37084597
The Na1.8 channel is a genetically validated target for pain and it is mostly expressed in the peripheral nervous system. Based on the disclosed structures of Na1.8-selective inhibitors, we designed...