Xue-Yin Pan
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Explore the profile of Xue-Yin Pan including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
300
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0
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Recent Articles
1.
Wang L, You H, Meng H, Pan X, Chen X, Bi Y, et al.
J Cell Physiol
. 2021 Oct;
237(2):1471-1485.
PMID: 34698390
Alcohol metabolism causes hepatocytes to release damage-associated molecular patterns (DAMPs). This includes mitochondrial DNA (mtDNA), which is generated and released from damaged hepatocytes and contributes to liver injury by producing...
2.
Pan X, Wang L, You H, Cheng M, Yang Y, Huang C, et al.
Lab Invest
. 2021 Jun;
101(9):1210-1224.
PMID: 34112940
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide. Macrophages exhibit different functional states and are classified as classically activated (M1) and alternatively activated (M2) macrophages....
3.
Pan X, Huang C, Li J
Int J Biol Sci
. 2021 Jan;
17(1):271-284.
PMID: 33390849
The 'epitranscriptome', a collective term for chemical modifications that influence the structure, metabolism, and functions of RNA, has recently emerged as vitally important for the regulation of gene expression. N-methyladenosine...
4.
Chen X, Li H, Bu F, Li X, Chen Y, Zhu S, et al.
Theranostics
. 2020 Apr;
10(11):4851-4870.
PMID: 32308754
: Circular RNAs (circRNAs) are a new form of noncoding RNAs that play crucial roles in various pathological processes. However, the expression profile and function of circRNAs in hepatic fibrosis...
5.
Chen X, Li X, Chen Y, Zhu S, Li H, Chen S, et al.
Int Immunopharmacol
. 2019 Sep;
76:105838.
PMID: 31473406
Hepatic fibrosis, a common pathological feature and leading cause of various chronic liver diseases, still lacks effective therapy. Hesperetin derivative (HD) is a derivative of Traditional Chinese Medicine monomer isolated...
6.
Pan X, You H, Wang L, Bi Y, Yang Y, Meng H, et al.
Theranostics
. 2019 Jul;
9(15):4308-4323.
PMID: 31285763
: Liver fibrosis is characterized by extensive deposition of extracellular matrix (ECM) components in the liver. RCAN1 (regulator of calcineurin 1), an endogenous inhibitor of calcineurin (CaN), is required for...
7.
Chen X, Chen Y, Huang H, Li H, Bu F, Pan X, et al.
Oncol Lett
. 2019 Jan;
17(2):1401-1408.
PMID: 30675193
The incidence of cancer is increasing at an alarming rate despite recent advances in prevention strategies, diagnostics and therapeutics for various types of cancer. The identification of novel biomarkers to...
8.
Yu H, Yao Y, Bu F, Chen Y, Wu Y, Yang Y, et al.
Mol Immunol
. 2019 Jan;
107:29-40.
PMID: 30639476
Yes-associated protein (YAP) is a significant downstream protein in the Hippo signaling pathway with important functions in cell proliferation, apoptosis, invasion and migration. YAP also plays a role in the...
9.
Chen X, Li W, Chen Y, Li X, Li H, Huang H, et al.
Cell Death Dis
. 2018 Oct;
9(10):1021.
PMID: 30282980
Hepatic myofibroblasts, activated hepatic stellate cells (HSCs), are the main cell type of extracellular matrix (ECM) deposition during hepatic fibrosis. Aberrant DNA methylation-regulated HSCs activation in liver fibrogenesis has been...
10.
Yang Y, Wu X, Li W, Huang H, Li H, Pan X, et al.
Oncogene
. 2018 Jul;
37(47):6119-6135.
PMID: 29993036
Macrophages play a crucial role in the progression of hepatic fibrosis (HF). In macrophages, epigenetic mechanisms are increasingly being recognized as crucial controllers of their phenotype. However, the functions of...