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Xuanxuan Nian

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Articles 25
Citations 129
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Recent Articles
1.
Zheng J, Li B, Jia L, Zhang J, Gong Z, Le Y, et al.
PLoS One . 2024 Dec; 19(12):e0311069. PMID: 39680522
Madin-Darby canine kidney (MDCK) cells are the recognized cell strain for influenza vaccine production. However, the tumorigenic potential of MDCK cells raises concerns about their use in biological product manufacturing....
2.
Zeng Z, Jia L, Zheng J, Nian X, Zhang Z, Chen L, et al.
J Med Virol . 2024 Oct; 96(10):e29858. PMID: 39370830
The COVID-19 pandemic had a significant impact on the global influenza vaccination and the epidemics of seasonal influenza. To further explore the molecular epidemiology of influenza viruses and assess vaccine...
3.
Cai M, Le Y, Gong Z, Dong T, Liu B, Su M, et al.
Vaccines (Basel) . 2024 Sep; 12(9). PMID: 39340023
Madin-Darby canine kidney (MDCK) cells are commonly used to produce cell-based influenza vaccines. However, the role of the low-serum medium on the proliferation of MDCK cells and the propagation of...
4.
Nian X, Liu H, Cai M, Duan K, Yang X
Vaccines (Basel) . 2024 Feb; 12(2). PMID: 38400201
The authors would like to make the following corrections to this published paper [...].
5.
Li F, Liu B, Xiong Y, Zhang Z, Zhang Q, Qiu R, et al.
Vaccines (Basel) . 2024 Feb; 12(2). PMID: 38400122
H5N1 highly pathogenic avian influenza virus (HPAIV) infections pose a significant threat to human health, with a mortality rate of around 50%. Limited global approval of H5N1 HPAIV vaccines, excluding...
6.
Wang X, Pu F, Yang X, Feng X, Zhang J, Duan K, et al.
Virulence . 2024 Jan; 15(1):2301242. PMID: 38170681
Influenza A virus (IAV) poses a threat to patients receiving immunosuppressive medications since they are more susceptible to infection with severe symptoms, and even death. Understanding the direct effects of...
7.
Liu Y, Zhang J, Liu W, Pan Y, Ruan S, Nian X, et al.
Emerg Microbes Infect . 2023 Nov; 13(1):2284297. PMID: 37970736
Following the national dynamic zero-COVID strategy adjustment, the utilization of broad-spectrum nasal neutralizing antibodies may offer an alternative approach to controlling the outbreak of Omicron variants between late 2022 and...
8.
Sun N, Zhang Y, Dong J, Liu G, Liu Z, Wang J, et al.
PeerJ . 2023 Sep; 11:e16077. PMID: 37744241
Background: Madin-Darby canine kidney (MDCK) cells are a cellular matrix in the production of influenza vaccines. The proliferation rate of MDCK cells is one of the critical factors that determine...
9.
Le Y, Zhang J, Gong Z, Zhang Z, Nian X, Li X, et al.
Heliyon . 2023 Sep; 9(9):e19246. PMID: 37681145
Tumor necrosis factor receptor-associated factor 3 (TRAF3), an adaptor protein, has significant and varying effects on immunity depending on cell types. The role of TRAF3 in Madin-Darby Canine Kidney Epithelial...
10.
Liu Z, Pei M, Liu G, Qiu Z, Wang S, Qiao Z, et al.
Biologicals . 2023 Aug; 83:101697. PMID: 37579524
MDCK is currently the main cell line used for influenza vaccine production in culture. Previous studies have reported that MDCK cells possess tumorigenic ability in nude mice. Although complete cell...