Xixi Xu
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Explore the profile of Xixi Xu including associated specialties, affiliations and a list of published articles.
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24
Citations
251
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Recent Articles
11.
Kong L, Valdivia D, Simon C, Hassinan C, Delestree N, Ramos D, et al.
Sci Transl Med
. 2021 Jan;
13(578).
PMID: 33504650
Gene replacement and pre-mRNA splicing modifier therapies represent breakthrough gene targeting treatments for the neuromuscular disease spinal muscular atrophy (SMA), but mechanisms underlying variable efficacy of treatment are incompletely understood....
12.
Xu X, Roseblade A, Rawling T, Ung A
RSC Med Chem
. 2021 Jan;
11(1):118-124.
PMID: 33479611
A library of novel tricyclic amides has been synthesised the Ritter reaction from β-caryophyllene and its monoepoxy derivative . The compounds were assessed for antiproliferative activities against the aggressive MDA-MB-231...
13.
Wanyan Y, Xu X, Liu K, Zhang H, Zhen J, Zhang R, et al.
Molecules
. 2020 Dec;
25(23).
PMID: 33297583
Inhibition of the glycolytic pathway is a critical strategy in anticancer therapy because of the role of aerobic glycolysis in cancer cells. The glycolytic inhibitor 2-Deoxy-d-glucose (2-DG) has shown potential...
14.
Zhang H, Han D, Lv T, Liu K, Yang Y, Xu X, et al.
Drug Des Devel Ther
. 2019 Jul;
13:2153-2167.
PMID: 31308628
There is an urgent need for the development of novel, effective, and less toxic drugs to treat leukemia. Antimicrobial peptides (AMPs) have received much more attention as alternative chemotherapeutic agents....
15.
Zhang F, Xu X, Huo Y, Xiao Y
Front Microbiol
. 2019 Jan;
9:3241.
PMID: 30666243
spp. are proposed as major plant growth-promoting fungi (PGPF) to increase plants growth and productivity. Mowing can stimulate aboveground regrowth to improve plant biomass and nutritional quality. However, the synergistic...
16.
Xu X, Ran J, Jiao L, Liang X, Zhao R
Food Res Int
. 2019 Jan;
115:580-588.
PMID: 30599982
Inhibition of spore germination or sterilization after induction of spore germination would effectively control low pH food spoilage caused by Alicyclobacillus acidoterrestris spores. However, the characteristics and mechanisms of A....
17.
Li C, Liu H, Yang Y, Xu X, Lv T, Zhang H, et al.
Front Pharmacol
. 2018 Nov;
9:1297.
PMID: 30483133
Development of antimicrobial peptides (AMPs) as highly effective and selective anticancer agents would represent great progress in cancer treatment. Here we show that myristoyl-CM4, a new synthetic analog generated by...
18.
Xu X, Rawling T, Roseblade A, Bishop R, Ung A
Medchemcomm
. 2018 Aug;
8(11):2105-2114.
PMID: 30108728
Tricyclic alkaloid-like compounds were synthesised in a few steps, the bridging Ritter reaction. The compounds were evaluated for their antiproliferative activity against the MCF-7 and the aggressive MDA-MB-231 breast cancer...
19.
Cao F, Wu H, Lv T, Yang Y, Li Y, Liu S, et al.
Fish Shellfish Immunol
. 2018 May;
79:73-78.
PMID: 29729312
Gamma-interferon-inducible lysosomal thiol reductase (GILT) plays an important role in the processing of major histocompatibility complex (MHC) class II-restricted antigens by catalyzing disulfide bonds reduction. Herein, a GILT homolog (ScGILT)...
20.
Eisenstein A, Gonzalez E, Raghunathan R, Xu X, Wu M, McLean E, et al.
Mol Diagn Ther
. 2018 Feb;
22(2):203-218.
PMID: 29411301
Earlier identification of aggressive melanoma remains a goal in the field of melanoma research. With new targeted and immune therapies that have revolutionized the care of patients with melanoma, the...