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Xiushan Wu

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Articles 112
Citations 1045
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Recent Articles
1.
Peng Z, Xu S, Wang H, Huang Y, Liu S, Jiao Z, et al.
Oncol Lett . 2025 Feb; 29(4):178. PMID: 39990806
Identifying the mechanism by which lipid metabolism regulates cancer may offer a novel approach for therapeutic intervention. It has previously been identified that a lipid metabolism-related factor, namely fatty acid...
2.
Li Y, Xu Y, Li R, Huang S, Wu Q, Yan J, et al.
Metabolites . 2024 Dec; 14(12). PMID: 39728461
General control nonderepressible 5 (Gcn5) is a lysine acetyltransferase (KAT) that is evolutionarily conserved across eukaryotes, with two homologs (Kat2a and Kat2b) identified in humans and one (Gcn5) in ....
3.
Fan X, Lei Y, Wang L, Wu X, Li D
Sci China Life Sci . 2024 Sep; 68(3):610-627. PMID: 39231901
The innovation of CRISPR/Cas gene editing technology has developed rapidly in recent years. It is widely used in the fields of disease animal model construction, biological breeding, disease diagnosis and...
4.
Li Y, Jiang Z, Xu Y, Yan J, Wu Q, Huang S, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892188
Pygopus (Pygo) has been identified as a specific nuclear co-activator of the canonical Wingless (Wg)/Wnt signaling pathway in . Pygo proteins consist of two conserved domains: an N-terminal homologous domain...
5.
Dong Y, Lu R, Cao H, Zhang J, Wu X, Deng Y, et al.
iScience . 2024 Jun; 27(6):109974. PMID: 38832028
Prader-Willi syndrome (PWS) is a genetic disorder characterized by behavioral disturbances, hyperphagia, and intellectual disability. Several surveys indicate that PWS is also associated with cardiac abnormalities, possibly contributing to a...
6.
Peng Z, Xu S, Zhang Q, Yang X, Yuan W, Wang Y, et al.
Exp Ther Med . 2023 Dec; 27(1):27. PMID: 38125362
The reprogramming of lipid metabolism serves an important role in occurrence and development of liver cancer. Fatty acid hydroxylase domain containing 2 (FAXDC2) is a hydroxylase involved in the synthesis...
7.
Cai W, Wang Y, Luo Y, Gao L, Zhang J, Jiang Z, et al.
Int J Mol Sci . 2023 Nov; 24(22). PMID: 38003559
Ankyrin repeat and suppression-of-cytokine-signaling box (Asb) proteins, a subset of ubiquitin ligase E3, include Asb5 with six ankyrin-repeat domains. Zebrafish harbor two gene isoforms, and . Currently, the effects of...
8.
Zhu Z, Zhu P, Fan X, Mo X, Wu X
Front Cell Dev Biol . 2023 Jul; 11:1093113. PMID: 37457298
Mesenchymal stem cells (MSCs) are one of the most potent therapeutic strategies for repairing cardiac injury. It has been shown in the latest studies that MSCs cannot survive in the...
9.
Shi Y, Qin B, Fan X, Li Y, Wang Y, Yuan W, et al.
Cell Tissue Res . 2023 May; 393(1):163-179. PMID: 37233752
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are used to regenerate the myocardium during cardiac repair after myocardial infarction. However, the regulatory mechanism underlying their ability to form mesodermal cells...
10.
Wen Y, Li Y, Yang B, Guo X, Lin L, Liang J, et al.
Dis Markers . 2022 Nov; 2022:6993994. PMID: 36398031
Abnormal activation of the classical Wnt pathway has been reported in non-small-cell lung cancer (NSCLC) previously. Pygo family genes, the core regulators of Wnt/-catenin signaling, were also reported to be...