Xinran Cai
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Explore the profile of Xinran Cai including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
208
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Recent Articles
1.
Pan B, Zhang Z, Ye D, Zhang X, Yao Y, Luo Y, et al.
JHEP Rep
. 2025 Jan;
7(1):101228.
PMID: 39802808
Background & Aims: The role of infiltrating neutrophils in hepatocellular carcinoma (HCC) is modulated by cellular metabolism, specifically lipid homeostasis. Throughout the progression of HCC, alterations in lipid metabolism are...
2.
Kim J, Tung H, Ke M, Xu P, Cai X, Xi Y, et al.
Hepatology
. 2024 Oct;
PMID: 39446334
Background Aims: Liver fibrosis is characterized by the progressive scarring of liver tissue. Oxidative stress is a critical causal factor of hepatic stellate cell (HSC) activation and the subsequent liver...
3.
Jiang L, Xie L, Wu Z, Ke Q, Chen M, Pan W, et al.
BMC Cancer
. 2024 Sep;
24(1):1191.
PMID: 39333917
Purpose: Identifying primary hepatic angiosarcoma (PHA) preoperatively is challenging, often relying on postoperative pathology. Invasive biopsy increases bleeding risk, emphasizing the importance of early PHA diagnosis through imaging. However, comprehensive...
4.
Tung H, Kim J, Zhu J, Li S, Yan J, Liu Q, et al.
Sci Transl Med
. 2024 Sep;
16(766):eadk8446.
PMID: 39321267
Activation of extracellular matrix-producing hepatic stellate cells (HSCs) is a key event in liver fibrogenesis. We showed that the expression of the heme-thiolate monooxygenase cytochrome P450 1B1 (CYP1B1) was elevated...
5.
Lin S, Hong J, Wu S, Zhu C, Liu F, Lin W, et al.
J Leukoc Biol
. 2024 Apr;
116(3):601-610.
PMID: 38626292
Conventional treatments have shown a limited efficacy for pancreatic cancer, and immunotherapy is an emerging option for treatment of this highly fatal malignancy. Neoantigen is critical to improving the efficacy...
6.
Wan Z, Huang H, West 3rd R, Zhang M, Zhang B, Cai X, et al.
Mater Today (Kidlington)
. 2024 Jan;
62:33-50.
PMID: 38239407
STING agonist has recently gained much attention for cancer treatment, but the therapeutic potential of STING agonist is hampered by STING-associated tumor immune resistance. In this work, guided by both...
7.
Lin S, Wang Y, Cai X, Ye Y, Chen Y
Int Immunopharmacol
. 2024 Jan;
128:111477.
PMID: 38183910
Hepatocellular carcinoma (HCC) exhibits high incidence and mortality rates in China. Most cases are often diagnosed at late stages and require multi-strategy therapies. In recent years, immune checkpoint inhibitors (ICIs),...
8.
Xu P, Cai X, Guan X, Xie W
Pharmacol Ther
. 2023 Sep;
251:108540.
PMID: 37777160
Protein sulfoconjugation, or sulfation, represents a critical post-translational modification (PTM) process that involves the attachment of sulfate groups to various positions of substrates within the protein peptides or glycoproteins. This...
9.
Cai X, Li S, Zeng X, Xu M, Wang Z, Singhi A, et al.
Cell Mol Gastroenterol Hepatol
. 2023 May;
16(3):473-495.
PMID: 37192689
Background & Aims: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths in the United States. Tyrosine sulfation, catalyzed by the tyrosylprotein sulfotransferase 2 (TPST2), is a...
10.
Cai X, Hong H, Chen Y
Ann Surg Oncol
. 2022 Dec;
30(4):1988-1989.
PMID: 36528747
No abstract available.