Xinqiang Huang
Overview
Explore the profile of Xinqiang Huang including associated specialties, affiliations and a list of published articles.
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14
Citations
660
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Recent Articles
1.
Huang X, Li L, Ammar R, Zhang Y, Wang Y, Ravi K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Nov;
316(2):L348-L357.
PMID: 30489156
The translation of novel pulmonary fibrosis therapies from preclinical models into the clinic represents a major challenge demonstrated by the high attrition rate of compounds that showed efficacy in preclinical...
2.
Huang X, Cai H, Ammar R, Zhang Y, Wang Y, Ravi K, et al.
Am J Physiol Gastrointest Liver Physiol
. 2018 Nov;
316(1):G15-G24.
PMID: 30406699
Precision-cut liver tissue slice (PCLS) contains all major cell types of the liver parenchyma and preserves the original cell-cell and cell-matrix contacts. It represents a promising ex vivo model to...
3.
Dhanasekaran R, Gabay-Ryan M, Baylot V, Lai I, Mosley A, Huang X, et al.
Oncotarget
. 2018 Feb;
9(5):5517-5528.
PMID: 29464015
Hepatocellular carcinoma (HCC) remains a significant clinical challenge with few therapeutic options. Genomic amplification and/or overexpression of the MYC oncogene is a common molecular event in HCC, thus making it...
4.
Huang X, Magnus J, Kaimal V, Karmali P, Li J, Walls M, et al.
Mol Cancer Ther
. 2017 Feb;
16(5):905-913.
PMID: 28167506
Hepatocellular carcinoma (HCC) is one of the most common human malignancies with poor prognosis and urgent unmet medical need. Aberrant expression of multiple members of the miR-17 family are frequently...
5.
Chau B, Xin C, Hartner J, Ren S, Castano A, Linn G, et al.
Sci Transl Med
. 2012 Feb;
4(121):121ra18.
PMID: 22344686
Scarring of the kidney is a major public health concern, directly promoting loss of kidney function. To understand the role of microRNA (miRNA) in the progression of kidney scarring in...
6.
Huang X, Gschweng E, Van Handel B, Cheng D, Mikkola H, Witte O
Blood
. 2010 Dec;
117(7):2157-65.
PMID: 21163928
MicroRNAs (miRs) play an important role in cell differentiation and maintenance of cell identity, but relatively little is known of their functional role in modulating human hematopoietic lineage differentiation. Human...
7.
Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan W
Mol Carcinog
. 2008 Nov;
48(6):553-62.
PMID: 19009564
Fibroblast growth factor (FGF) family signaling mediates cell-to-cell communication in development and organ homeostasis in adults. Of the FGF receptor (FGFR) isotypes, FGFR4 is the sole resident isotype present in...
8.
FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver
Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan W
Diabetes
. 2007 Aug;
56(10):2501-10.
PMID: 17664243
Objective: Fibroblast growth factor (FGF) family signaling largely controls cellular homeostasis through short-range intercell paracrine communication. Recently FGF15/19, 21, and 23 have been implicated in endocrine control of metabolic homeostasis....
9.
Luo Y, Huang X, McKeehan W
Arch Biochem Biophys
. 2007 Mar;
460(1):17-24.
PMID: 17346663
Heparinase I from Flavobacterium heparinum, a source of diverse polysaccharidases, suffers from low yields, insufficient purity for structural studies and insolubility when expressed as a recombinant product in Escherichia coli...
10.
Huang X, Yu C, Jin C, Yang C, Xie R, Cao D, et al.
Mol Carcinog
. 2006 Aug;
45(12):934-42.
PMID: 16929488
Inappropriate fibroblast growth factor (FGF) signaling is involved in most tissue-specific pathologies including cancer. Previously we showed that inappropriate expression and chronic activity of FGF receptor (FGFR) 1 in hepatocytes...