Xinping Tan
Overview
Explore the profile of Xinping Tan including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
1142
Followers
0
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Recent Articles
1.
Ma J, Tan X, Kwon Y, Delgado E, Zarnegar A, DeFrances M, et al.
Cell Mol Gastroenterol Hepatol
. 2021 Nov;
13(2):565-582.
PMID: 34756982
Background & Aims: Nonalcoholic fatty liver disease is a frequent cause of hepatic dysfunction and is now a global epidemic. This ailment can progress to an advanced form called nonalcoholic...
2.
Seneviratne D, Ma J, Tan X, Kwon Y, Muhammad E, Melhem M, et al.
Gastroenterology
. 2014 Sep;
148(1):181-191.e17.
PMID: 25244939
Background & Aims: Genomic instability promotes colon carcinogenesis by inducing genetic mutations, but not all genes affected by this process have been identified. We investigated whether genomic instability in human...
3.
Ma J, Zou C, Guo L, Seneviratne D, Tan X, Kwon Y, et al.
Hepatology
. 2013 Oct;
59(5):2010-21.
PMID: 24122846
Unlabelled: Met, the transmembrane tyrosine kinase receptor for hepatocyte growth factor (HGF), is known to function as a potent antiapoptotic mediator in normal and neoplastic cells. Herein we report that...
4.
Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia
Gupta N, Krasnodembskaya A, Kapetanaki M, Mouded M, Tan X, Serikov V, et al.
Thorax
. 2012 Jan;
67(6):533-9.
PMID: 22250097
Rationale: Bacterial pneumonia is the most common infectious cause of death worldwide and treatment is increasingly hampered by antibiotic resistance. Mesenchymal stem cells (MSCs) have been demonstrated to provide protection...
5.
A hepatocyte growth factor receptor (Met)-insulin receptor hybrid governs hepatic glucose metabolism
Fafalios A, Ma J, Tan X, Stoops J, Luo J, DeFrances M, et al.
Nat Med
. 2011 Nov;
17(12):1577-84.
PMID: 22081023
Met is the transmembrane tyrosine kinase cell surface receptor for hepatocyte growth factor (HGF) and is structurally related to the insulin receptor (INSR) tyrosine kinase. Here we report that the...
6.
Zhang X, Tan X, Zeng G, Misse A, Singh S, Kim Y, et al.
Hepatology
. 2010 Jun;
52(3):954-65.
PMID: 20583210
Unlabelled: Activation of beta-catenin, the central effector of the canonical Wnt pathway and a recognized oncogene, has been implicated in hepatocellular carcinoma. We examined N-nitrosodiethylamine (DEN)-induced tumorigenesis in hepatic beta-catenin...
7.
Nejak-Bowen K, Zeng G, Tan X, Cieply B, Monga S
J Biol Chem
. 2009 Aug;
284(41):28115-28127.
PMID: 19690176
Because the Wnt/beta-catenin pathway plays multiple roles in liver pathobiology, it is critical to identify gene targets that mediate such diverse effects. Here we report a novel role of beta-catenin...
8.
Tan X, Yuan Y, Zeng G, Apte U, Thompson M, Cieply B, et al.
Hepatology
. 2008 Apr;
47(5):1667-79.
PMID: 18393386
Unlabelled: Beta-catenin, the central component of the canonical Wnt pathway, plays important roles in the processes of liver regeneration, growth, and cancer. Previously, we identified temporal expression of beta-catenin during...
9.
Stock P, Monga D, Tan X, Micsenyi A, Loizos N, Monga S
Mol Cancer Ther
. 2007 Jul;
6(7):1932-41.
PMID: 17604334
Hepatocellular cancer (HCC) is a disease of poor prognosis. Identifying novel molecular aberrations might present opportunities to identify new therapeutic targets. Due to the similarities between the processes of development...
10.
Zeng G, Awan F, Otruba W, Muller P, Apte U, Tan X, et al.
Hepatology
. 2006 Dec;
45(1):195-204.
PMID: 17187422
Unlabelled: The Wnt signaling pathway is essential for a wide array of developmental and physiological processes. Wnts are extracellular ligands that bind to frizzled (Fz) receptors at the membrane, canonically...