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Xinjian Yu

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Articles 51
Citations 671
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Recent Articles
1.
Yu X, Sarabia S, Urbicain M, Somvanshi S, Patel R, Tran T, et al.
bioRxiv . 2025 Jan; PMID: 39763896
Most malignant hepatocellular tumors in children are classified as either hepatoblastoma (HB) or hepatocellular carcinoma (HCC), but some tumors demonstrate features of both HB and HCC. These tumors have been...
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Pan J, Tan Y, Shan L, Seery S, Deng B, Ling Z, et al.
Nat Med . 2024 Oct; 31(1):352. PMID: 39415025
No abstract available.
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Pan J, Tan Y, Shan L, Seery S, Deng B, Ling Z, et al.
Nat Med . 2024 Oct; 31(1):126-136. PMID: 39354195
Refractory or relapsed T cell acute lymphoblastic leukemia (r/r T-ALL) patients have poor prognoses, due to the lack of effective salvage therapies. Recently, CD7-targeting chimeric antigen receptor (CAR)-T therapies show...
5.
Song Z, Huo Y, Wu Q, Yu X, Yang Y, Meng Z, et al.
Heliyon . 2024 Sep; 10(17):e37135. PMID: 39296054
The de Winter electrocardiogram (ECG) pattern indicates severe stenosis or occlusion of the left anterior descending artery (LAD). We present a 72-year-old female with 1.5-h chest pain. Angiography and optical...
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Zhao L, Li C, Zuo S, Han Y, Deng B, Ling Z, et al.
Mol Ther . 2024 Sep; PMID: 39244642
Chimeric antigen receptor (CAR)-T cell therapy showed preliminary activity in patients with refractory or relapsed T cell acute lymphoblastic leukemia (r/r T-ALL). However, many obstacles remain, including manufacturing difficulties and...
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Zuo S, Li C, Sun X, Deng B, Zhang Y, Han Y, et al.
Nat Commun . 2024 Jul; 15(1):6155. PMID: 39039086
Chimeric antigen receptor (CAR) T cells show suboptimal efficacy in acute myeloid leukemia (AML). We find that CAR T cells exposed to myeloid leukemia show impaired activation and cytolytic function,...
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Li X, Zhao X, Yu X, Zhao J, Fang X
J Bioinform Comput Biol . 2024 Jul; 22(4):2450016. PMID: 39036847
The Qingfei Paidu decoction (QFPDD) is a widely acclaimed therapeutic formula employed nationwide for the clinical management of coronavirus disease 2019 (COVID-19). QFPDD exerts a synergistic therapeutic effect, characterized by...
9.
Jiang C, Lin B, Ye X, Yu Y, Xu P, Peng C, et al.
J Affect Disord . 2024 Jun; 360:336-344. PMID: 38824965
Background: The absence of clinically-validated biomarkers or objective protocols hinders effective major depressive disorder (MDD) diagnosis. Compared to healthy control (HC), MDD exhibits anomalies in plasma protein levels and neuroimaging...
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Espinoza A, Patel R, Patel K, Badachhape A, Whitlock R, Srivastava R, et al.
J Hepatol . 2024 Jan; 80(4):610-621. PMID: 38242326
Background & Aims: Patients with metastatic, treatment-refractory, and relapsed hepatoblastoma (HB) have survival rates of less than 50% due to limited treatment options. To develop new therapeutic strategies for these...