Xingcheng Chen
Overview
Explore the profile of Xingcheng Chen including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
601
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Recent Articles
1.
He C, Lv X, Liu J, Ruan J, Chen P, Huang C, et al.
EMBO Rep
. 2024 Sep;
25(10):4542-4569.
PMID: 39271776
High grade serous ovarian carcinoma (HGSOC) is the most common and aggressive ovarian malignancy. Accumulating evidence indicates that HGSOC may originate from human fallopian tube epithelial cells (FTECs), although the...
2.
Mo Y, Zhu Z, Tan J, Liang Z, Wu J, Chen X, et al.
Front Neurol
. 2022 Sep;
13:985499.
PMID: 36158953
The revised WHO guidelines on multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB) include linezolid in the core drug group. Common adverse events of prolonged linezolid use are bone marrow suppression and peripheral...
3.
Lv X, He C, Huang C, Hua G, Chen X, Timm B, et al.
Sci Bull (Beijing)
. 2021 Dec;
65(15):1281-1296.
PMID: 34888112
Understanding the cell-of-origin of ovarian high grade serous cancer (HGSC) is the prerequisite for efficient prevention and early diagnosis of this most lethal gynecological cancer. Recently, a mesenchymal type of...
4.
Lv X, He C, Huang C, Wang H, Hua G, Wang Z, et al.
FASEB J
. 2019 Jun;
33(9):10049-10064.
PMID: 31199671
Although the role of the Hippo signaling pathway in development and tumorigenesis has been extensively studied in multiple organs, its role in ovarian follicle development remains largely unknown. Here, we...
5.
He C, Lv X, Huang C, Angeletti P, Hua G, Dong J, et al.
Cell Rep
. 2019 Mar;
26(10):2636-2650.e5.
PMID: 30840887
HPV infections are common in healthy women and only rarely cause cervical cancer, suggesting that individual genetic susceptibility may play a critical role in the establishment of persistent HPV infection...
6.
He C, Lv X, Huang C, Hua G, Ma B, Chen X, et al.
EMBO Rep
. 2019 Feb;
20(3).
PMID: 30755404
Dysfunction of the homeostasis-maintaining systems in specific cell types or tissues renders the organism susceptible to a range of diseases, including cancers. One of the emerging mechanisms for maintaining tissue...
7.
Wang Z, Chen X, Zhong M, Yang S, Zhou J, Klinkebiel D, et al.
Cell Signal
. 2018 Sep;
52:137-146.
PMID: 30223016
YES is a member of the SRC family kinase (SFK) group of non-receptor tyrosine kinases, which are implicated in multiple key cellular processes involved in oncogenesis. Antitubulin agents have been...
8.
Zhou J, Zeng Y, Cui L, Chen X, Stauffer S, Wang Z, et al.
Proc Natl Acad Sci U S A
. 2018 Jul;
115(29):E6760-E6769.
PMID: 29967145
Zyxin is a member of the focal adhesion complex and plays a critical role in actin filament polymerization and cell motility. Several recent studies showed that Zyxin is a positive...
9.
Stauffer S, Zeng Y, Zhou J, Chen X, Chen Y, Dong J
Cell Signal
. 2017 Aug;
39:74-83.
PMID: 28780319
PDZ-binding kinase (PBK) plays a major role in proliferation and in safeguarding mitotic fidelity in cancer cells. Frequently upregulated in many cancers, PBK drives tumorigenesis and metastasis. PBK has been...
10.
Zeng Y, Stauffer S, Zhou J, Chen X, Chen Y, Dong J
J Biol Chem
. 2017 Jul;
292(36):15028-15038.
PMID: 28739871
The Hippo pathway is an evolutionarily conserved signaling pathway that plays important roles in stem cell biology, tissue homeostasis, and cancer development. Vestigial-like 4 (Vgll4) functions as a transcriptional co-repressor...