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Xin Chou

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Articles 9
Citations 90
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Recent Articles
1.
Chou X, Fang M, Shen Y, Jiang C, Miao L, Yang L, et al.
Ecotoxicol Environ Saf . 2024 Nov; 287:117316. PMID: 39520747
Background: The concurrent effects of particulate matter (PM) on both blood pressure (BP) and short-chain fatty acids (SCFAs) are insufficiently explored, with limited research on the potential mediating roles of...
2.
Chou X, Li X, Ma K, Shen Y, Min Z, Xiao W, et al.
Sci Total Environ . 2023 Sep; 904:166955. PMID: 37704144
Cadmium (Cd) is a commonly found environmental pollutant and is known to damage multiple organs with kidneys being the most common one. N-methyl-d-aspartate receptor 1 (NMDAR1) is a ligand-gated ion...
3.
Chou X, Li X, Min Z, Ding F, Ma K, Shen Y, et al.
Ecotoxicol Environ Saf . 2022 Sep; 245:114098. PMID: 36137422
Cadmium (Cd), the common environmental pollutant, primarily targets at renal proximal tubules and induces nephrotoxicity. Cellular senescence, a phenomenon of cell growth arrest and a characteristics of maladaptive cell self-repair,...
4.
Chou X, Ma K, Shen Y, Min Z, Wu Q, Sun D
Toxicology . 2021 Apr; 456:152769. PMID: 33813002
Cadmium (Cd) is a nephrotoxicant that primarily damages renal proximal tubular cells. Endoplasmic reticulum (ER) stress is mechanistically linked to Cd-induced renal injury. Inositol-requiring enzyme 1 (IRE-1α) is the most...
5.
Wei C, Gu S, Ren J, Gu Y, Xu X, Chou X, et al.
Neurooncol Adv . 2020 Jul; 1(1):vdz037. PMID: 32642666
The immune system plays an essential role in the development of tumors, which has been demonstrated in multiple types of cancers. Consistent with this, immunotherapies with targets that disrupt these...
6.
Gao H, Chen J, Ding F, Chou X, Zhang X, Wan Y, et al.
J Appl Toxicol . 2019 Mar; 39(8):1096-1107. PMID: 30907447
Glyphosate-based herbicides have been used worldwide for decades and have been suggested to induce nephrotoxicity, but the underlying mechanism is not yet clear. In this study, we treated a human...
7.
Chou X, Ding F, Zhang X, Ding X, Gao H, Wu Q
Arch Toxicol . 2019 Feb; 93(4):965-986. PMID: 30796460
Cadmium (Cd), an occupational and environmental pollutant, induces nephrotoxicity by primarily damaging renal proximal tubular cells. In this study, we hypothesized that pyroptosis, a caspase-1-dependent inflammatory programmed cell death mechanism,...
8.
Ji X, Chou X, Ge Z, Ding F, Gao H, Wu Q
J Appl Toxicol . 2018 Mar; 38(8):1091-1103. PMID: 29578247
The mechanism of male reproductive toxicity induced by benzo[a]pyrene (BaP) is poorly understood. Gap junctional intercellular communication (GJIC) is known to play a critical role in maintaining spermatogenesis. The aim...
9.
Wang Q, Chou X, Guan F, Fang Z, Lu S, Lei J, et al.
Sci Rep . 2017 Mar; 7(1):230. PMID: 28331224
Liver fibrosis is the most serious pathology caused by Schistosoma japonicum infection, which arises when schistosome eggs are deposited in the liver. Eosinophils, macrophages and hepatic stellate cells (HSCs) have...