Xin-Yuan Lei
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Explore the profile of Xin-Yuan Lei including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
23
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Recent Articles
1.
Lei X, He K, Li Q, Zhang L, Wu D, Yang J, et al.
Clin Transl Med
. 2024 Dec;
14(12):e70111.
PMID: 39690136
As a chromatin remodelling factor, high mobility group A1 (HMGA1) plays various roles in both physiological and pathological conditions. However, its role in DNA damage response and DNA damage-based chemotherapy...
2.
Zhao Y, Liu M, Zhang L, Yang Q, Sun Q, Guo J, et al.
Nat Commun
. 2024 Nov;
15(1):9909.
PMID: 39548107
Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to meet the high energy and biosynthetic demands required for their proliferation. High mobility group A1 (HMGA1) is a structural...
3.
Liu M, Zhao Y, Li Q, Lei X, He K, Guo J, et al.
Cell Death Dis
. 2024 Jul;
15(7):541.
PMID: 39080260
Esophageal squamous cell carcinoma (ESCC) possesses a poor prognosis and treatment outcome. Dysregulated metabolism contributes to unrestricted growth of multiple cancers. However, abnormal metabolism, such as highly activated pentose phosphate...
4.
Guo J, He K, Yuan J, An W, Yin W, Li Q, et al.
Int J Biol Sci
. 2024 May;
20(7):2640-2657.
PMID: 38725843
Esophageal carcinoma is amongst the prevalent malignancies worldwide, characterized by unclear molecular classifications and varying clinical outcomes. The PI3K/AKT/mTOR signaling, one of the frequently perturbed dysregulated pathways in human malignancies,...
5.
Yang J, Lei X, He K, Guo J, Liu M, Li J, et al.
Cell Death Dis
. 2024 Feb;
15(2):158.
PMID: 38383528
Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC). Resistance to chemotherapeutic drugs is an important hurdle to effective treatment. Understanding the mechanisms underlying chemotherapy resistance in ESCC...
6.
He K, Lei X, Zhang L, Wu D, Li J, Lu L, et al.
Front Microbiol
. 2023 Dec;
14:1278479.
PMID: 38156008
Background: Emerging evidence reveals that SARS-CoV-2 possesses the capability to disrupt the gastrointestinal (GI) homeostasis, resulting in the long-term symptoms such as loss of appetite, diarrhea, gastroesophageal reflux, and nausea....
7.
He K, Lei X, Wu D, Zhang L, Li J, Li Q, et al.
Gut Microbes
. 2023 Dec;
15(2):2293312.
PMID: 38087436
Intestinal dysbiosis frequently occurs in abdominal radiotherapy and contributes to irradiation (IR)-induced intestinal damage and inflammation. () is a recently characterized probiotic, which is critical for maintaining the dynamics of...