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Jin-Rong Guo

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Articles 10
Citations 36
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Recent Articles
1.
Han J, Wang Y, Liu C, Liu F, Guo J, Zhu W, et al.
Fa Yi Xue Za Zhi . 2025 Feb; 40(5):461-467. PMID: 39992338
Objectives: To verify the stability and accuracy of the made-in-China Quick TargSeq Fully Integrated Automated On-site Rapid DNA Detection Instrument (hereinafter referred to as Quick TargSeq DNA detection instrument) and...
2.
Cao P, Liu Y, Ni Z, Zhang M, Wei H, Liu A, et al.
Sci Adv . 2025 Jan; 11(4):eadq3874. PMID: 39841840
Prosocial behaviors are advantageous to social species, but the neural mechanism(s) through which others receive benefit remain unknown. Here, we found that bystander mice display rescue-like behavior (tongue dragging) toward...
3.
Lei X, He K, Li Q, Zhang L, Wu D, Yang J, et al.
Clin Transl Med . 2024 Dec; 14(12):e70111. PMID: 39690136
As a chromatin remodelling factor, high mobility group A1 (HMGA1) plays various roles in both physiological and pathological conditions. However, its role in DNA damage response and DNA damage-based chemotherapy...
4.
Zhao Y, Liu M, Zhang L, Yang Q, Sun Q, Guo J, et al.
Nat Commun . 2024 Nov; 15(1):9909. PMID: 39548107
Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to meet the high energy and biosynthetic demands required for their proliferation. High mobility group A1 (HMGA1) is a structural...
5.
Zhu M, Dong W, Guo J, Huang J, Cheng P, Yang Y, et al.
Adv Sci (Weinh) . 2024 Nov; 12(1):e2406766. PMID: 39487959
Aromatic essential oils have been shown to relieve anxiety and enhance relaxation, although the neural circuits underlying these effects have remained unknown. Here, it is found that treatment with 1.0%...
6.
Liu M, Zhao Y, Li Q, Lei X, He K, Guo J, et al.
Cell Death Dis . 2024 Jul; 15(7):541. PMID: 39080260
Esophageal squamous cell carcinoma (ESCC) possesses a poor prognosis and treatment outcome. Dysregulated metabolism contributes to unrestricted growth of multiple cancers. However, abnormal metabolism, such as highly activated pentose phosphate...
7.
Guo J, He K, Yuan J, An W, Yin W, Li Q, et al.
Int J Biol Sci . 2024 May; 20(7):2640-2657. PMID: 38725843
Esophageal carcinoma is amongst the prevalent malignancies worldwide, characterized by unclear molecular classifications and varying clinical outcomes. The PI3K/AKT/mTOR signaling, one of the frequently perturbed dysregulated pathways in human malignancies,...
8.
Yang J, Lei X, He K, Guo J, Liu M, Li J, et al.
Cell Death Dis . 2024 Feb; 15(2):158. PMID: 38383528
Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC). Resistance to chemotherapeutic drugs is an important hurdle to effective treatment. Understanding the mechanisms underlying chemotherapy resistance in ESCC...
9.
Yang J, Liu M, Lv L, Guo J, He K, Zhang H, et al.
Front Microbiol . 2022 Oct; 13:932294. PMID: 36312920
Abdominal irradiation (IR) destroys the intestinal mucosal barrier, leading to severe intestinal infection. There is an urgent need to find safe and effective treatments to reduce IR-induced intestinal injury. In...
10.
Wang K, He K, Yang J, Liu M, Guo J, Liang J, et al.
Front Cell Dev Biol . 2022 Mar; 10:842153. PMID: 35300424
Deficiency in T cell-mediated adaptive immunity, such as low CD8 T cell infiltration, inhibits the immune surveillance, promotes malignant transformation, and facilitates tumor growth. Microbiota dysbiosis diminishes the immune system...