Xiechao He
Overview
Explore the profile of Xiechao He including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
324
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0
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Recent Articles
1.
Liu Y, Luo X, Sun Y, Chen K, Hu T, You B, et al.
Dev Cell
. 2024 Oct;
60(3):414-428.e8.
PMID: 39481377
Understanding the cellular and genetic mechanisms driving human-specific features of cortical development remains a challenge. We generated a cell-type resolved atlas of transcriptome and chromatin accessibility in the developing macaque...
2.
Cui G, Feng S, Yan Y, Wang L, He X, Li X, et al.
Cell Rep
. 2022 Aug;
40(9):111285.
PMID: 36044859
During mammalian embryogenesis, spatial regulation of gene expression and cell signaling are functionally coupled with lineage specification, patterning of tissue progenitors, and germ layer morphogenesis. While the mouse model has...
3.
Luo X, Liu Y, Dang D, Hu T, Hou Y, Meng X, et al.
Cell
. 2021 Jan;
184(3):723-740.e21.
PMID: 33508230
Elucidating the regulatory mechanisms of human brain evolution is essential to understanding human cognition and mental disorders. We generated multi-omics profiles and constructed a high-resolution map of 3D genome architecture...
4.
Luo X, He Y, Zhang C, He X, Yan L, Li M, et al.
Nat Commun
. 2019 Dec;
10(1):5525.
PMID: 31797925
CRISPR-Cas9 is a widely-used genome editing tool, but its off-target effect and on-target complex mutations remain a concern, especially in view of future clinical applications. Non-human primates (NHPs) share close...
5.
Ma H, Zhai J, Wan H, Jiang X, Wang X, Wang L, et al.
Science
. 2019 Nov;
366(6467).
PMID: 31672918
Gastrulation is a key event in embryonic development when the germ layers are specified and the basic animal body plan is established. The complexities of primate gastrulation remain a mystery...
6.
Liu D, Wang X, He D, Sun C, He X, Yan L, et al.
Genome Res
. 2018 Aug;
28(10):1481-1493.
PMID: 30154223
Naive pluripotency exists in epiblast cells of mouse pre-implantation embryos. However, whether the naive pluripotency is transient or nonexistent in primate embryos remains unclear. Using RNA-seq in single blastomeres from...
7.
Wang X, Liu D, He D, Suo S, Xia X, He X, et al.
Genome Res
. 2017 Sep;
27(9):1621.2.
PMID: 28864552
No abstract available.
8.
Wang X, Liu D, He D, Suo S, Xia X, He X, et al.
Genome Res
. 2017 Feb;
27(4):567-579.
PMID: 28223401
Preimplantation embryogenesis encompasses several critical events including genome reprogramming, zygotic genome activation (ZGA), and cell-fate commitment. The molecular basis of these processes remains obscure in primates in which there is...
9.
Chen Y, Niu Y, Yang S, He X, Ji S, Si W, et al.
Am J Primatol
. 2012 Apr;
74(2):165-73.
PMID: 22512020
Much effort has been focused on improving assisted reproductive technology procedures in humans and nonhuman primates (NHPs). However, the pregnancy rate after embryo transfer (ET) has not been satisfactory, indicating...
10.
Wei Q, Sun Z, He X, Tan T, Lu B, Guo X, et al.
PLoS One
. 2011 Oct;
6(9):e25052.
PMID: 21966410
Parthenogenetic embryonic stem cells are considered as a promising resource for regeneration medicine and powerful tools for developmental biology. A lot of studies have revealed that embryonic stem cells have...