Weizhi Ji
Overview
Explore the profile of Weizhi Ji including associated specialties, affiliations and a list of published articles.
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Articles
131
Citations
3187
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Recent Articles
1.
Wu R, Li P, Xiao P, Zhang S, Wang X, Liu J, et al.
Nat Commun
. 2025 Mar;
16(1):2398.
PMID: 40064877
Activation of endogenous full-length utrophin, a dystrophin homolog, presents an attractive therapeutic strategy for Duchenne muscular dystrophy (DMD), regardless of mutation types and loci. However, current dCas9-based activators are too...
2.
Wu J, Shao T, Tang Z, Liu G, Li Z, Shi Y, et al.
Nat Commun
. 2025 Jan;
16(1):1130.
PMID: 39875393
Blastoids-blastocyst-like structures created in vitro-emerge as a valuable model for early embryonic development research. Non-human primates stem cell-derived blastoids are an ethically viable alternative to human counterparts, yet the low...
3.
Liu S, Yang N, Yan Y, Wang S, Chen J, Wang Y, et al.
Cell Rep Methods
. 2024 Oct;
4(10):100876.
PMID: 39413778
The etiology of Parkinson's disease (PD) remains elusive, and the limited availability of suitable animal models hampers research on pathogenesis and drug development. We report the development of a cynomolgus...
4.
Ren S, Fu X, Guo W, Bai R, Li S, Zhang T, et al.
Cell
. 2024 Sep;
187(23):6669-6686.e16.
PMID: 39305903
Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease caused by mutations in the DMD gene. Muscle fibers rely on the coordination of multiple cell types for repair and regenerative...
5.
Yao J, Dai S, Zhu R, Tan J, Zhao Q, Yin Y, et al.
Elife
. 2024 Apr;
12.
PMID: 38607670
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on...
6.
Luo X, Jia H, Wang F, Mo H, Kang Y, Zhang N, et al.
JACC Basic Transl Sci
. 2024 Apr;
9(3):380-395.
PMID: 38559624
To solve the clinical transformation dilemma of lamin A/C (LMNA)-mutated dilated cardiomyopathy (LMD), we developed an LMNA-mutated primate model based on the similarity between the phenotype of primates and humans....
7.
Wu J, Shi Y, Yang S, Tang Z, Li Z, Li Z, et al.
Med Rev (2021)
. 2024 Jan;
3(4):277-304.
PMID: 38235400
The remarkable similarity between non-human primates (NHPs) and humans establishes them as essential models for understanding human biology and diseases, as well as for developing novel therapeutic strategies, thereby providing...
8.
Wei Y, Zhang E, Yu L, Ci B, Sakurai M, Guo L, et al.
Cell
. 2023 Dec;
186(26):5859-5875.e24.
PMID: 38052213
Embryogenesis necessitates harmonious coordination between embryonic and extraembryonic tissues. Although stem cells of both embryonic and extraembryonic origins have been generated, they are grown in different culture conditions. In this...
9.
Zhang H, Li J, Yu Y, Ren J, Liu Q, Bao Z, et al.
Cell Rep
. 2023 Nov;
42(11):113396.
PMID: 37910499
No abstract available.
10.
Wu J, Kang Y, Luo X, Dai S, Shi Y, Li Z, et al.
Protein Cell
. 2023 Sep;
15(3):207-222.
PMID: 37758041
Non-human primates (NHPs) are increasingly used in preclinical trials to test the safety and efficacy of biotechnology therapies. Nonetheless, given the ethical issues and costs associated with this model, it...