Xiayun Wan
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Explore the profile of Xiayun Wan including associated specialties, affiliations and a list of published articles.
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36
Citations
264
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Recent Articles
1.
Yue Y, Wan X, Liu G, Zhu T, Xu D, Zhao M, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2025 Jan;
137:111260.
PMID: 39855536
3,4-Methylenedioxymethamphetamine (MDMA) is a widely recognized entactogen frequently used recreationally. It is known for its interaction with the serotonin and oxytocin systems, which underlie its entactogenic effects in humans. Recently,...
2.
Xu D, Eguchi A, Murayama R, Liu G, Zhao M, Zhu T, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2024 Dec;
136():111223.
PMID: 39701173
3,4-Methylenedioxymethamphetamine (MDMA; Ecstasy) is a widely abused recreational drug that has also gained interest for potential clinical applications in mental health. With the growing recognition of gut microbiota's role in...
3.
Liu G, Ma L, Sakamoto A, Fujimura L, Xu D, Zhao M, et al.
Pharmacol Biochem Behav
. 2024 Nov;
245():173906.
PMID: 39549733
Arketamine, the (R)-enantiomer of ketamine, exhibits both therapeutic and sustained prophylactic effects in an inflammation-driven model of depression, although the precise mechanisms remain elusive. Given the involvement of γδ T...
4.
Wang Y, Qin X, Shuai J, Wan X, Yu D, Ling L, et al.
Inflammation
. 2024 Nov;
PMID: 39538091
Pristimerin is a pentacyclic triterpenoid mainly derived from Celastraceae plants such as Maytenus ilicifolia, which has been traditionally used for the treatment of gastrointestinal disorders. Pharmacological studies have shown that...
5.
Zhao M, Zhu T, Xu D, Wan X, Liu G, Murayama R, et al.
Eur J Pharmacol
. 2024 Nov;
985:177096.
PMID: 39500390
The novel antidepressant arketamine, the (R)-enantiomer of ketamine, has been shown to ameliorate demyelination and facilitate remyelination in the brains of cuprizone (CPZ)-treated mice. However, the mechanisms behind its effects...
6.
Xu D, Liu G, Zhao M, Wan X, Qu Y, Murayama R, et al.
J Affect Disord
. 2024 Sep;
367:745-755.
PMID: 39236893
Background: Chronic restrain stress (CRS) induces depression-like behaviors and demyelination in the brain; however, the relationship between these depression-like behaviors and demyelination remains unclear. Arketamine, the (R)-enantiomer of ketamine, has...
7.
Lv M, Wan X, Wang Y, Jiang H, Qin X, Wang Z, et al.
J Pharm Biomed Anal
. 2024 Jul;
249:116351.
PMID: 39018720
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that primarily affects mucosa and submucosa of colon and rectum. Although the exact etiology of UC remains elusive, increasing evidence...
8.
Ma L, Eguchi A, Liu G, Qu Y, Wan X, Murayama R, et al.
Pharmacol Biochem Behav
. 2024 Feb;
238:173736.
PMID: 38401573
The gut-brain axis, which includes gut microbiota and microbiome-derived metabolites, might be implicated in depression. We reported the sustained prophylactic effects of a new antidepressant arketamine in chronic restrain stress...
9.
Qu Y, Eguchi A, Ma L, Wan X, Mori C, Hashimoto K
Neurobiol Dis
. 2023 Nov;
189:106348.
PMID: 37956855
3,4-Methylenedioxymethamphetamine (MDMA) is the most widely used illicit substance worldwide. Nevertheless, recent observational studies demonstrated that lifetime MDMA use among U.S. adults was associated with a lower risk of depression...
10.
Yang Y, Eguchi A, Wan X, Mori C, Hashimoto K
J Affect Disord
. 2023 Oct;
345:157-167.
PMID: 37879416
Depression is a frequent symptom in patients with chronic liver disease; however, the mechanisms underlying this association remain unclear. Dysbiosis of gut microbiota plays a critical role in depression through...