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Xiaorong Lin

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Articles 154
Citations 3441
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Recent Articles
11.
Glueck N, Xie X, Lin X
Cell Rep . 2024 Oct; 43(11):114904. PMID: 39475508
Cryptococcus neoformans, the causative agent of cryptococcosis and a representative of the Basidiomycota phylum of Fungi, is a valuable model for our understanding of eukaryotic/fungal biology. Negative feedback is a...
12.
Matha A, Xie X, Maier R, Lin X
PLoS Genet . 2024 Sep; 20(9):e1011413. PMID: 39283915
Nickel (Ni) is an abundant element on Earth and it can be toxic to all forms of life. Unlike our knowledge of other metals, little is known about the biochemical...
13.
Chadwick B, Ristow L, Xie X, Krysan D, Lin X
Nat Microbiol . 2024 Sep; 9(10):2684-2695. PMID: 39232204
Cryptococcus neoformans is a ubiquitous soil fungus and airborne pathogen that causes over 180,000 deaths each year. Cryptococcus must adapt to host CO levels to cause disease, but the genetic...
14.
Matha A, Xie X, Lin X
J Fungi (Basel) . 2024 Aug; 10(8). PMID: 39194920
We recently discovered that the D4H sterol biosensor strains used in Figure 4 of the published paper [...].
15.
Lin X, He K, Gu Z, Zhao X
Trends Pharmacol Sci . 2024 Aug; 45(9):824-838. PMID: 39129061
Human physiology is profoundly influenced by the gut microbiota, which generates a wide array of metabolites. These microbiota-derived compounds serve as signaling molecules, interacting with various cellular targets in the...
16.
Lin X, Zhang Y, Huang H, Zhuang W, Wu L
Expert Opin Drug Saf . 2024 Jul; :1-12. PMID: 39083397
Background: The Phosphoinositide 3-kinases (PI3Ks) family plays a crucial role in tumorigenesis. Alpelisib (inhibiting PI3Kα), copanlisib (inhibiting PI3Kα andPI3Kδ), duvelisib (inhibiting PI3Kδ and PI3Kγ), and idelalisib (inhibiting PI3Kδ) were developed...
17.
Pham T, Shi R, Ambati S, Meagher R, Lin X
iScience . 2024 Jul; 27(7):110349. PMID: 39055951
Systemic cryptococcosis is often fatal even with the current antifungal therapy and there is no vaccine available. Induction therapy with amphotericin B (AmB) is essential for its treatment, which can...
18.
Lin X, Cai F, Lin J, Zhang K, Lin Y
Anal Methods . 2024 Jun; 16(27):4619-4625. PMID: 38920338
The degree of the carbohydrate antigen 125 (CA-125) level in serum is positively correlated with the severity of ovarian cancer. In this study, a facile photoelectrochemical (PEC) immunoassay was devised...
19.
Chadwick B, Lin X
Curr Opin Microbiol . 2024 May; 79:102488. PMID: 38759247
Carbon dioxide supplies carbon for photosynthetic species and is a major product of respiration for all life forms. Inside the human body where CO is a by-product of the tricarboxylic...
20.
Chen X, Tu Q, Zhao W, Lin X, Chen Z, Li B, et al.
Food Chem Toxicol . 2024 May; 189:114738. PMID: 38754806
5-hydroxymethylfurfural is a common byproduct in food. However, its effect on growth and development remains incompletely understood. This study investigated the developmental toxicity of 5-HMF to Drosophila larvae. The growth...