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Xiaoming Zha

Explore the profile of Xiaoming Zha including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 802
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Recent Articles
1.
Li C, Lan X, Li X, Fu Y, Gui G, Li X, et al.
J Med Chem . 2025 Jan; 68(2):1222-1244. PMID: 39760448
Methionine adenosyltransferase 2A (MAT2A) has emerged as a synthetic lethal drug target in cancers bearing homozygous methylthioadenosine phosphorylase (MTAP) gene deletion. Despite the remarkable progress in the discovery and development...
2.
Chen L, Li H, Zhang H, Yang H, Qian J, Li Z, et al.
JAMA . 2024 Dec; 333(8):673-681. PMID: 39671272
Importance: Preferred neoadjuvant strategies for early or locally advanced triple-negative breast cancer include a 4-drug chemotherapy regimen containing anthracyclines, cyclophosphamide, taxanes, and platinum. Blockade of the programmed death receptor 1/ligand-1...
3.
Xu Y, Huang L, Wang J, He J, Wang Y, Zhang W, et al.
BMC Cancer . 2024 Nov; 24(1):1387. PMID: 39533204
Background: Pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) is a treatment for preventing febrile neutropenia (FN) in patients with early breast cancer. However, the optimal injection timing of PEG-rhG-CSF after...
4.
Yao Q, Du Y, Liu W, Liu X, Zhang M, Zha H, et al.
Acad Radiol . 2024 Nov; PMID: 39523140
Rationale And Objectives: To construct a radiomics nomogram derived from multiparametric ultrasound (US) imaging using the SHapley Additive exPlanations (SHAP) method for the accurate identification of residual axillary lymph node...
5.
Shi W, He J, Li X, Zha H, Chen R, Xu L, et al.
Int J Med Sci . 2024 Nov; 21(14):2714-2724. PMID: 39512684
This study aimed to develop a combined ultrasound (US)-pathology model to predict the axillary status more accurately after NST in breast cancer. This retrospective study included breast cancer patients who...
6.
Zhong H, Li P, Yan Q, Xia Y, Zhang X, Lai Y, et al.
J Med Chem . 2024 Nov; 67(21):19323-19341. PMID: 39485487
Vitiligo is the most common cause of depigmentation worldwide, with immunosuppressive treatments often being inefficient and prone to recurrence, making it essential to identify new therapeutic targets. Periplakin (PPL) has...
7.
Li X, Wang L, Wang Y, Ma L, Zheng R, Ding J, et al.
BMJ Open . 2024 Sep; 14(9):e087700. PMID: 39260835
Introduction: Sentinel lymph node biopsy (SLNB) is a standard procedure for patients with clinically assessed negative axillary lymph nodes (cN0) during early-stage breast cancer (EBC). However, the majority of EBC...
8.
Gao Y, Zhang M, Sun G, Ma L, Nie J, Yuan Z, et al.
Breast . 2024 Jun; 76:103762. PMID: 38924994
Background: Male breast cancer (MBC) is a rare disease. Although several large-scale studies have investigated MBC patients in other countries, the features of MBC patients in China have not been...
9.
Wan X, Shi W, Ma L, Wang L, Zheng R, He J, et al.
Clin Transl Med . 2024 May; 14(5):e1681. PMID: 38725048
Background: We explored the potential novel anticancer mechanisms of 25-hydroxyvitamin D (25(OH)D), a vitamin D metabolite with antitumour effects in breast cancer. It is stable in serum and is used...
10.
Wen F, Gui G, Wang X, Qin A, Ma T, Chen H, et al.
J Med Chem . 2024 Apr; 67(11):8667-8692. PMID: 38651495
The targeting of cancer cell intrinsic metabolism has emerged as a promising strategy for antitumor intervention. In the study, we identified the first-in-class small molecules that effectively inhibit both mutant...