Xiaojuan Ran
Overview
Explore the profile of Xiaojuan Ran including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
264
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0
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Recent Articles
1.
Ran X, Hu A, Kuang Y, Wang C, Liu W, Xiao X, et al.
Breast Cancer Res Treat
. 2024 Jun;
207(2):405-415.
PMID: 38874684
Purpose: Breast cancer is the most frequent cancer in women with significant death rate. Morbidity is associated with drug resistance and metastasis. Development of novel drugs is unmet need. The...
2.
Zhong Y, Le H, Zhang X, Dai Y, Guo F, Ran X, et al.
J Hematol Oncol
. 2024 May;
17(1):36.
PMID: 38783389
Oncolytic viruses (OVs) offer a novel approach to treat solid tumors; however, their efficacy is frequently suboptimal due to various limiting factors. To address this challenge, we engineered an OV...
3.
Kawale A, Ran X, Patel P, Saxena S, Lawrence M, Zou L
Sci Adv
. 2024 Jan;
10(3):eadk2771.
PMID: 38241374
Mutation signatures associated with apolipoprotein B mRNA editing catalytic polypeptide-like 3A/B (APOBEC3A/B) cytidine deaminases are prevalent across cancers, implying their roles as mutagenic drivers during tumorigenesis and tumor evolution. APOBEC3A...
4.
Ran X, Zheng J, Chen L, Xia Z, Wang Y, Sun C, et al.
Cancer Immunol Res
. 2023 Dec;
12(2):232-246.
PMID: 38091354
Isocitrate dehydrogenase (IDH)-wild-type (WT) high-grade gliomas, especially glioblastomas, are highly aggressive and have an immunosuppressive tumor microenvironment. Although tumor-infiltrating immune cells are known to play a critical role in glioma...
5.
Wang M, Ran X, Leung W, Kawale A, Saxena S, Ouyang J, et al.
Genes Dev
. 2023 Nov;
37(19-20):929-943.
PMID: 37932012
The mismatch repair (MMR) deficiency of cancer cells drives mutagenesis and offers a useful biomarker for immunotherapy. However, many MMR-deficient (MMR-d) tumors do not respond to immunotherapy, highlighting the need...
6.
Yang H, Lachtara E, Ran X, Hopkins J, Patel P, Zhu X, et al.
Nat Commun
. 2023 Sep;
14(1):6114.
PMID: 37777505
The roles of R-loops and RNA modifications in homologous recombination (HR) and other DNA double-stranded break (DSB) repair pathways remain poorly understood. Here, we find that DNA damage-induced RNA methyl-5-cytosine...
7.
Zhong H, Ran X, Chen B, Xiong Y, Yu X
ACS Chem Neurosci
. 2023 Aug;
14(18):3409-3417.
PMID: 37647501
Cognitive dysfunction induced by anesthesia in the infant is a crucial clinical issue that is still being debated and the focus of concern for the parents. However, the mechanism of...
8.
Ran X, Tang T, Wang M, Ye L, Zhuang Y, Zhao F, et al.
aBIOTECH
. 2022 Oct;
2(4):357-364.
PMID: 36311809
Supplementary Information: The online version contains supplementary material available at 10.1007/s42994-021-00048-z.
9.
Chen S, Zheng Y, Ran X, Du H, Feng H, Yang L, et al.
Cell Res
. 2021 Sep;
31(12):1291-1307.
PMID: 34518654
Intestinal stem cell (ISC) differentiation is regulated precisely by a niche in the crypt, where lymphocytes may interact with stem and transient amplifying (TA) cells. However, whether and how lymphocyte-stem/TA...
10.
Lu Q, Liu J, Zhao S, Gomez Castro M, Laurent-Rolle M, Dong J, et al.
Immunity
. 2021 May;
54(6):1304-1319.e9.
PMID: 34048708
Despite mounting evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) engagement with immune cells, most express little, if any, of the canonical receptor of SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2)....