Xiaojie Meng
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Explore the profile of Xiaojie Meng including associated specialties, affiliations and a list of published articles.
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19
Citations
405
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Recent Articles
11.
Dai Y, DeSano J, Tang W, Meng X, Meng Y, Burstein E, et al.
PLoS One
. 2010 Dec;
5(12):e14153.
PMID: 21170316
Background: Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human malignancies, especially the androgen-independent prostate cancer (AIPC) with constitutive NF-κB activation. Celastrol induces apoptosis by means...
12.
Kikuchi K, Tancharoen S, Matsuda F, Biswas K, Ito T, Morimoto Y, et al.
Biochem Biophys Res Commun
. 2009 Sep;
390(4):1121-5.
PMID: 19737535
Aquaporin-4 (AQP4) plays a role in the generation of post-ischemic edema. Pharmacological modulation of AQP4 function may thus provide a novel therapeutic strategy for the treatment of stroke, tumor-associated edema,...
13.
Nawa Y, Kawahara K, Tancharoen S, Meng X, Sameshima H, Ito T, et al.
J Leukoc Biol
. 2009 Jul;
86(3):645-53.
PMID: 19581374
NPM is a major nucleolar multifunctional protein involved in ribosome biogenesis, centrosome duplication, cell-cycle progression, apoptosis, cell differentiation, and sensing cellular stress. Alarmins are endogenous molecules released from activated cells...
14.
Meng X, Kawahara K, Matsushita K, Nawa Y, Shrestha B, Kikuchi K, et al.
Biochem Biophys Res Commun
. 2009 Jun;
387(1):42-6.
PMID: 19559007
1,5-anhydro-d-fructose (1,5-AF), a monosaccharide formed from starch and glycogen, exhibits antioxidant and antibacterial activity, and inhibits cytokine release by attenuating NF-kappaB activation in LPS-stimulated mice. The present study examined whether...
15.
Kikuchi K, Kawahara K, Biswas K, Ito T, Tancharoen S, Morimoto Y, et al.
Biochem Biophys Res Commun
. 2009 Apr;
385(2):132-6.
PMID: 19379716
High mobility group box-1 (HMGB1), a non-histone DNA-binding protein, is massively released into the extracellular space from neuronal cells after ischemic insult and exacerbates brain tissue damage in rats. Minocycline...
16.
Kawahara K, Hashiguchi T, Masuda K, Saniabadi A, Kikuchi K, Tancharoen S, et al.
Int J Mol Med
. 2009 Apr;
23(5):615-20.
PMID: 19360320
High mobility group box-1 protein (HMGB1), primarily from the nucleus, is released into the extracellular milieu either passively from necrotic cells or actively through secretion by monocytes/macrophages. Extracellular HMGB1 acts...
17.
Meng X, Kawahara K, Nawa Y, Miura N, Shrestha B, Tancharoen S, et al.
Biochem Biophys Res Commun
. 2009 Jan;
380(2):343-8.
PMID: 19174150
Lipopolysaccharide (LPS) stimulates macrophages by activating NF-kappaB, which contributes to the release of tumor necrosis factor (TNF)-alpha and interleukin (IL)-6. 1,5-Anhydro-D-fructose (1,5-AF), a monosaccharide formed from starch and glycogen, exhibits...
18.
Kawahara K, Hashiguchi T, Kikuchi K, Tancharoen S, Miura N, Ito T, et al.
Int J Mol Med
. 2008 Oct;
22(5):639-44.
PMID: 18949384
High mobility group box 1 (HMGB1) is a non-histone nuclear protein which is released from the nucleus of activated macrophages into the extracellular space in response to stimuli such as...
19.
Ito T, Kawahara K, Okamoto K, Yamada S, Yasuda M, Imaizumi H, et al.
Arterioscler Thromb Vasc Biol
. 2008 Jul;
28(10):1825-30.
PMID: 18599803
Objective: High mobility group box 1 protein (HMGB1) was identified as a mediator of endotoxin lethality. We previously reported that thrombomodulin (TM), an endothelial thrombin-binding protein, bound to HMGB1, thereby...