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Teruto Hashiguchi

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Articles 114
Citations 1506
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Recent Articles
1.
Higashi S, Yamakuchi M, Hashinokuchi H, Takenouchi K, Tabaru A, Oyama Y, et al.
PLoS One . 2025 Feb; 20(2):e0318811. PMID: 39992949
The acidic tumor microenvironment plays a critical role in the malignant transformation of cancer cells. One mechanism underlying this transformation involves epithelial-mesenchymal transition (EMT). This is induced by prolonged exposure...
2.
Kawamura J, Yamakuchi M, Ueno K, Hashiguchi T, Okamoto Y
Sci Rep . 2025 Feb; 15(1):4138. PMID: 39900983
The detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA)...
3.
Matsushita K, Ishige T, Watanabe K, Akahane T, Tanimoto A, Yoshimoto M, et al.
Sci Rep . 2025 Jan; 15(1):1036. PMID: 39762492
Comprehensive genomic profiling (CGP) is increasingly used as a clinical laboratory test and being applied to cancer treatment; however, standardization and external quality assessments (EQA) have not been fully developed....
4.
Okawa M, Yamakuchi M, Bibek A, Takenouchi K, Maywar D, Yamada S, et al.
PLoS One . 2024 Dec; 19(12):e0316035. PMID: 39700124
Background: VEGF-A concentrations were measured in the blood of bevacizumab-treated cancer patients in previous studies, but a consensus has not formed that would develop VEGF-A into a clinical biomarker. Recently,...
5.
Hamada Y, Tanoue K, Arigami T, Yamakuchi M, Okawa M, Matsushita D, et al.
Cancers (Basel) . 2024 Dec; 16(23). PMID: 39682145
Background/objectives: The response rate to immune checkpoint inhibitor (ICI) therapy is limited. Further, there is a need to discover biomarkers to predict therapeutic efficacy. The vascular endothelial growth factor (VEGF)...
6.
Arima N, Fujisaki M, Nakabeppu S, Shima K, Hayashida M, Kamada Y, et al.
Rinsho Ketsueki . 2024 Feb; 65(1):13-17. PMID: 38311383
A 24-year-old man was found to have an ileocecal ulcer by colonoscopy. A pathological diagnosis of diffuse large B-cell lymphoma (DLBCL) with diffuse positive reaction of Epstein-Barr encoding region (EBER)...
7.
Higashi Y, Yamakuchi M, Ibusuki A, Okubo A, Fukushige T, Hashiguchi T, et al.
J Invest Dermatol . 2023 Dec; 144(7):1471-1478.e6. PMID: 38157932
The pathological hallmark of psoriasis is the infiltration of neutrophils into the skin. Some neutrophil-derived microRNAs (miRNAs) serve as biomarkers for various diseases, but none have been reported for psoriasis....
8.
Kawasaki H, Fudamoto K, Yamamoto M, Iwaanakuchi T, Yoshida T, Hashiguchi T, et al.
Medicine (Baltimore) . 2023 Sep; 102(35):e34632. PMID: 37657061
This study aimed to clarify the relationship between the sequential organ failure assessment (SOFA) score and the length of intensive care unit (ICU) and hospital stays and verify whether the...
9.
Yamakuchi M, Okawa M, Takenouchi K, Bibek A, Yamada S, Inoue K, et al.
PLoS One . 2023 Apr; 18(4):e0284131. PMID: 37027444
Vascular endothelial growth factor A (VEGF-A) plays pivotal roles in regulating tumor angiogenesis as well as physiological vascular function. The major VEGF-A isoforms, VEGF-A121 and VEGF-A165, in serum, plasma, and...
10.
Nagata R, Matsuura E, Nozuma S, Dozono M, Noguchi Y, Ando M, et al.
Front Neurol . 2023 Mar; 14:1137958. PMID: 36860574
Objective: Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR) antibodies; however, several studies have reported that individuals...