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Xiao Yun Xu

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Articles 93
Citations 761
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Recent Articles
1.
Zhu Y, Armour C, Li B, Pirola S, Salmasi Y, Athanasiou T, et al.
Biomech Model Mechanobiol . 2025 Mar; PMID: 40067580
This study aimed to characterize the altered hemodynamics and wall mechanics in ascending thoracic aortic aneurysms (ATAA) by employing fully coupled two-way fluid-structure interaction (FSI) analyses. Our FSI models incorporated...
2.
Troulliotis G, Duncan A, Xu X, Gandaglia A, Naso F, Versteeg H, et al.
Med Eng Phys . 2024 Dec; 134:104255. PMID: 39672658
In the past two decades there has been rapid development in the field of computational cardiac models. These have included either (i) mechanical models that assumed simultaneous myocardial activation, or...
3.
Zhu Y, Pirola S, Salmasi M, Sasidharan S, Fisichella S, ORegan D, et al.
Cardiovasc Eng Technol . 2024 Oct; 16(1):52-65. PMID: 39455477
Purpose: Finite element analysis (FEA) has been used to predict wall stress in ascending thoracic aortic aneurysm (ATAA) in order to evaluate risk of dissection or rupture. Patient-specific FEA requires...
4.
Yin Z, Armour C, Kandail H, ORegan D, Bahrami T, Mirsadraee S, et al.
Int J Numer Method Biomed Eng . 2024 Aug; 40(11):e3865. PMID: 39209425
The opening and closing dynamics of the aortic valve (AV) has a strong influence on haemodynamics in the aortic root, and both play a pivotal role in maintaining normal physiological...
5.
Wang K, Armour C, Guo B, Dong Z, Xu X
Int J Numer Method Biomed Eng . 2024 Jul; 40(9):e3855. PMID: 39051141
Computational fluid dynamics (CFD) simulations have shown great potentials in cardiovascular disease diagnosis and postoperative assessment. Patient-specific and well-tuned boundary conditions are key to obtaining accurate and reliable hemodynamic results....
6.
Yuan X, Kan X, Li J, Yan Y, Mirsadraee S, Mittal T, et al.
Eur Heart J Imaging Methods Pract . 2024 Jul; 2(1):qyae007. PMID: 39045205
Aims: Aortic root motion is suspected to contribute to proximal aortic dissection. While motion of the aorta in four dimensions can be traced with real-time imaging, displacement and rotation in...
7.
Yang Y, Gu B, Xu X
Comput Biol Med . 2024 Feb; 171:108141. PMID: 38367449
The synergistic advantage of combining tissue plasminogen activator (tPA) with pro-urokinase (proUK) for thrombolysis has been demonstrated in several in vitro experiments, and a single site proUK mutant (m-proUK) has...
8.
Manchester E, Pirola S, Pirola S, Mastroiacovo G, Polvani G, Pontone G, et al.
Comput Biol Med . 2024 Feb; 171:108123. PMID: 38354498
Aortic valve disease is often treated with bioprosthetic valves. An alternative treatment is aortic valve neocuspidization which is a relatively new reparative procedure whereby the three aortic cusps are replaced...
9.
Kan X, Ma T, Jiang X, Holzapfel G, Dong Z, Xu X
Comput Methods Programs Biomed . 2023 Dec; 244:107994. PMID: 38159449
Background And Objective: Although thoracic aortic endovascular repair (TEVAR) has shown promising outcomes in the treatment of patients with complicated type B aortic dissection, complications still occur after TEVAR that...
10.
Watson C, Saaid H, Vedula V, Cardenas J, Henke P, Nicoud F, et al.
Ann Biomed Eng . 2023 Nov; 52(3):467-486. PMID: 37914979
Venous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions of patients globally. VTE is a particularly consequential pathology, as incidence is correlated with extremely common risk factors, and...