Xiao C Li
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Explore the profile of Xiao C Li including associated specialties, affiliations and a list of published articles.
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47
Citations
1370
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Recent Articles
11.
Ferrao F, Cardoso L, Drummond H, Li X, Zhuo J, Gomes D, et al.
Am J Physiol Renal Physiol
. 2017 May;
313(2):F440-F449.
PMID: 28468964
ANG II has many biological effects in renal physiology, particularly in Ca handling in the regulation of fluid and solute reabsorption. It involves the systemic endocrine renin-angiotensin system (RAS), but...
12.
Li X, Zhuo J
Curr Hypertens Rep
. 2016 Jul;
18(8):63.
PMID: 27372447
It is well recognized that the renin-angiotensin system (RAS) exists not only as circulating, paracrine (cell to cell), but also intracrine (intracellular) system. In the kidney, however, it is difficult...
13.
Zhuo J, Kobori H, Li X, Satou R, Katsurada A, Navar L
Am J Physiol Renal Physiol
. 2016 Feb;
310(10):F1103-12.
PMID: 26864937
Long-term angiotensin II (ANG II) infusion significantly increases ANG II levels in the kidney through two major mechanisms: AT1 receptor-mediated augmentation of angiotensinogen (AGT) expression and uptake of circulating ANG...
14.
Li X, Shull G, Miguel-Qin E, Chen F, Zhuo J
Physiol Rep
. 2015 Nov;
3(11).
PMID: 26564064
The role of Na(+/)H(+) exchanger 3 (NHE3) in the kidney in angiotensin II (ANG II)-induced hypertension remains unknown. The present study used global NHE3-deficient mice with transgenic rescue of the...
15.
Li X, Shull G, Miguel-Qin E, Zhuo J
Physiol Genomics
. 2015 Aug;
47(10):479-87.
PMID: 26242933
The renal mechanisms responsible for angiotensin II (ANG II)-induced hypertension remain incompletely understood. The present study tested the hypothesis that the Na(+)/H(+) exchanger 3 (NHE3) is required for ANG II-induced...
16.
Li X, Gu V, Miguel-Qin E, Zhuo J
Am J Physiol Renal Physiol
. 2014 Aug;
307(8):F949-61.
PMID: 25164083
Caveolin 1 (CAV-1) functions not only as a constitutive scaffolding protein of caveolae but also as a vesicular transporter and signaling regulator. In the present study, we tested the hypothesis...
17.
Li X, Zhuo J
Am J Physiol Renal Physiol
. 2014 Apr;
307(2):F222-33.
PMID: 24740791
The present study tested the hypothesis that the multiligand endocytic receptor megalin is partially involved in the uptake of ANG II and downstream signaling responses in mouse proximal tubule cells...
18.
Zhuo J, Ferrao F, Zheng Y, Li X
Front Endocrinol (Lausanne)
. 2013 Nov;
4:166.
PMID: 24273531
The renin-angiotensin system (RAS) is well-recognized as one of the oldest and most important regulators of arterial blood pressure, cardiovascular, and renal function. New frontiers have recently emerged in the...
19.
Li X, Zhuo J
Curr Hypertens Rep
. 2013 Sep;
15(5):522-30.
PMID: 23996678
Type 2 diabetes is well recognized as a noninsulin-dependent diabetic disease. Clinical evidence indicates that the level of circulating insulin may be normal, subnormal, and even elevated in type 2...
20.
Zhuo J, Li X
Compr Physiol
. 2013 Jul;
3(3):1079-123.
PMID: 23897681
The kidney plays a fundamental role in maintaining body salt and fluid balance and blood pressure homeostasis through the actions of its proximal and distal tubular segments of nephrons. However,...