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Xiao-Yuan Mao

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Articles 70
Citations 1266
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Recent Articles
1.
Dai W, Zhu Y, Jiang Z, Xiang Y, Mao X, Liu Z
CNS Neurosci Ther . 2025 Feb; 31(2):e70253. PMID: 39915895
Background: Berberine (BBR) has been reported to mitigate epileptic seizures. However, the potential mechanism of its anti-seizure effect remains uncharacterized. Aims: This study aimed to investigate the protective effect of...
2.
Cao D, Zhou X, Guo Q, Xiang M, Bao M, He B, et al.
Biomark Res . 2024 Nov; 12(1):142. PMID: 39563472
Epilepsy remains a prevalent chronic neurological disease that is featured by aberrant, recurrent and hypersynchronous discharge of neurons and poses a great challenge to healthcare systems. Although several therapeutic interventions...
3.
Li Q, Huang Y, Li Q, Jia J, Liu Z, Zhou H, et al.
Neuroreport . 2024 Oct; 35(17):1090-1097. PMID: 39423328
The objective of this study is to explore whether sodium valproate (VPA) alleviates epileptic seizures via suppressing lysyl oxidase (Lox)-mediated ferroptosis. Epileptic seizure mouse model was prepared via intrahippocampal injection...
4.
Wang Z, Liu J, Jiang S, Zhuo W, Xie P, Dai W, et al.
CNS Neurosci Ther . 2024 Aug; 30(8):e14911. PMID: 39145422
Background: Epilepsy is a widespread central nervous system disorder with an estimated 50 million people affected globally. It is characterized by a bimodal incidence peak among infants and the elderly...
5.
Chen K, Peng Q, Cao D, Wang Z, Zhang K, Zhou X, et al.
Brain Res Bull . 2024 Mar; 210:110928. PMID: 38493836
Epilepsy-associated cognitive disorder (ECD), a prevalent comorbidity in epilepsy patients, has so far uncharacterized etiological origins. Our prior work revealed that lysyl oxidase (Lox) acted as a novel contributor of...
6.
Liu R, Zou Y, Wang W, Chen J, Zhang L, Feng J, et al.
Nat Commun . 2023 Nov; 14(1):7421. PMID: 37973916
The gut microbiota may have an effect on the therapeutic resistance and toxicity of immune checkpoint inhibitors (ICIs). However, the associations between the highly variable genomes of gut bacteria and...
7.
Wang Z, Guan Q, Zhou H, Mao X, Chen F
Genes Dis . 2023 Jul; 10(3):771-785. PMID: 37396555
Vascular remodeling and angiogenesis are two key processes in the maintenance of vascular homeostasis and involved in a wide array of vascular pathologies. Following these processes, extracellular matrix (ECM) provides...
8.
Zheng J, Zhu T, Zhuo W, Mao X, Yin J, Li X, et al.
Biochem Pharmacol . 2023 May; 213:115616. PMID: 37211173
Cancer stem cells (CSCs) are the leading cause of recurrence and poor prognosis in non-small cell lung cancer (NSCLC). Eukaryotic translation initiation factor 3a (eIF3a) participates in many tumor development...
9.
Xia Q, Yu J, Wang Z, Guan Q, Mao X
Front Pharmacol . 2022 Sep; 13:990461. PMID: 36160460
: Previous investigations have illustrated that lysyl oxidase family enzymes (LOXs) are contributing factors for tumor progression and remodeling immunomicroenvironment. However, it is scarce regarding comprehensive analysis of LOXs in...
10.
Yang N, Zhang K, Guan Q, Wang Z, Chen K, Mao X
Antioxidants (Basel) . 2022 Aug; 11(8). PMID: 36009321
Repetitive seizures, a common phenomenon in diverse neurologic conditions such as epilepsy, can undoubtedly cause neuronal injury and our prior work reveals that ferroptosis is a contributing factor of neuronal...