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Xiao-Yi Yang

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Articles 48
Citations 714
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Recent Articles
1.
Trotter T, Wilson A, McBane J, Dagotto C, Yang X, Wei J, et al.
Cancer Res Commun . 2024 Apr; 4(4):1050-1062. PMID: 38592453
Significance: Multitolerant NoGlow mice enable tracking and gene manipulation of transplanted tumor cells without immune-mediated rejection, thus providing a platform to investigate novel mechanisms of adaptive immunity related to metastasis,...
2.
Dailey G, Rabiola C, Lei G, Wei J, Yang X, Wang T, et al.
Hum Vaccin Immunother . 2024 Feb; 20(1):2309693. PMID: 38330990
ER+ breast cancers (BC) are characterized by the elevated expression and signaling of estrogen receptor alpha (, which renders them sensitive to anti-endocrine therapy. While these therapies are clinically effective,...
3.
Kaneko K, Nagata H, Yang X, Ginzel J, Hartman Z, Everitt J, et al.
Cancers (Basel) . 2022 Dec; 14(23). PMID: 36497243
Ductal carcinoma in situ (DCIS) of the breast is often managed by lumpectomy and radiation or mastectomy, despite its indolent features. Effective non-invasive treatment strategies could reduce the morbidity of...
4.
Hwang B, Tsao L, Acharya C, Trotter T, Agarwal P, Wei J, et al.
J Immunother Cancer . 2022 Apr; 10(3). PMID: 35361727
Background: The majority of colorectal carcinomas (CRCs) are insensitive to programmed death protein-1/programmed death-ligand 1 (anti-PD-1/PD-L1) immune checkpoint inhibitor (ICI) antibodies. While there are many causes for ICI insensitivity, recent...
5.
Fan M, Duan Y, Li N, Yang X, Ma J, Gong Z, et al.
Zhongguo Zhong Yao Za Zhi . 2022 Mar; 47(5):1350-1358. PMID: 35343164
This study aims to identify the active components and the mechanism of Jingqi Yukui Capsules(JQYK) in the treatment of gastric ulcer based on network pharmacology, and verify some key targets...
6.
Osada T, Crosby E, Kaneko K, Snyder J, Ginzel J, Acharya C, et al.
Mol Cancer Ther . 2021 Oct; 21(1):217-226. PMID: 34675120
A noninvasive test to discriminate indolent prostate cancers from lethal ones would focus treatment where necessary while reducing overtreatment. We exploited the known activity of heat shock protein 90 (Hsp90)...
7.
Werner L, Gibson K, Goodman M, Helm D, Walter K, Holloran S, et al.
J Immunother Cancer . 2021 May; 9(5). PMID: 33958486
Background: Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor...
8.
Crosby E, Acharya C, Haddad A, Rabiola C, Lei G, Wei J, et al.
Clin Cancer Res . 2020 Aug; 26(17):4670-4681. PMID: 32732224
Purpose: Despite promising advances in breast cancer immunotherapy, augmenting T-cell infiltration has remained a significant challenge. Although neither individual vaccines nor immune checkpoint blockade (ICB) have had broad success as...
9.
Chen A, Xu R, Wang T, Wei J, Yang X, Liu C, et al.
J Immunother Cancer . 2020 Jun; 8(1). PMID: 32532838
Background: The advent of immune checkpoint blockade antibodies has demonstrated that effective mobilization of T cell responses can cause tumor regression of metastatic cancers, although these responses are heterogeneous and...
10.
Kaneko K, Osada T, Morse M, Gwin W, Ginzel J, Snyder J, et al.
Commun Biol . 2020 May; 3(1):226. PMID: 32385408
Photodynamic therapy (PDT) ablates malignancies by applying focused near-infrared (nIR) light onto a lesion of interest after systemic administration of a photosensitizer (PS); however, the accumulation of existing PS is...