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Xiao-Juan Du

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Articles 24
Citations 186
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Recent Articles
11.
Liu W, Wang N, Lu M, Du X, Xing B
Mol Med Rep . 2016 Jun; 14(2):1617-23. PMID: 27315121
Methyl-CpG binding domain 2 (MBD2) leads to the silencing of methylated genes in cancer cells and was implicated in the activation of prometastatic genes in hepatocellular carcinoma (HCC). The present...
12.
Tao Y, Fang F, Hu S, Lu J, Cao L, Zhao W, et al.
BMC Cancer . 2015 Oct; 15:756. PMID: 26490736
Background: Acute myeloid leukemia (AML) is the second-most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature of AML. GATA4 has been suggested to be...
13.
Lu J, Tao Y, Li Z, Cao L, Hu S, Wang N, et al.
Cancer Cell Int . 2015 Jul; 15:44. PMID: 26136641
Background: Wilms' tumor (WT) is one of the most common malignant neoplasms of the urinary tract in children. Anaplastic histology (unfavorable histology) accounts for about 10% of whole WTs, and...
14.
Tao Y, Xu L, Lu J, Hu S, Fang F, Cao L, et al.
J Exp Clin Cancer Res . 2015 Jan; 34:4. PMID: 25609158
Background: Pediatric acute myeloid leukemia (AML) comprises up to 20% of all childhood leukemia. Recent research shows that aberrant DNA methylation patterning may play a role in leukemogenesis. The epigenetic...
15.
Wang N, Li Z, Zhao H, Tao Y, Xu L, Lu J, et al.
Int J Mol Sci . 2015 Jan; 16(1):1266-92. PMID: 25574601
Polo-like kinase 1 (PLK1) is highly expressed in many cancers and therefore a biomarker of transformation and potential target for the development of cancer-specific small molecule drugs. RO3280 was recently...
16.
Tao Y, Hu S, Lu J, Cao L, Zhao W, Xiao P, et al.
Int J Mol Med . 2014 Oct; 34(6):1505-15. PMID: 25319049
Acute myeloid leukemia (AML) is the second-most common form of leukemia in children. Aberrant DNA methylation patterns are characteristic of AML. Zinc finger protein 382 (ZNF382) has been suggested to...
17.
Tao Y, Xu L, Lu J, Cao L, Li Z, Hu S, et al.
J Transl Med . 2014 Jun; 12:182. PMID: 24962166
Background: Acute myeloid leukemia (AML) is the second most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature in various tumors, including AML. Metallothionein III...
18.
Tao Y, Pang L, Du X, Sun L, Hu S, Lu J, et al.
Int J Mol Sci . 2013 Feb; 14(2):3376-94. PMID: 23389039
Histone modification enzymes regulate gene expression by altering the accessibility of promoters to transcription factors. We sought to determine whether the genes encoding histone modification enzymes are dysregulated in pediatric...
19.
Zhang L, Yuan X, Chen Y, Du X, Yu S, Yang M
Gene . 2013 Jan; 517(1):60-4. PMID: 23313300
Aim: As a novel molecularly targeting agent for non-small-cell lung cancer (NSCLC), Gefitinib can block its tyrosine kinase activity of the epidermal growth factor receptor (EGFR). Genetic variations in EGFR...
20.
Tao Y, Lu J, Du X, Sun L, Zhao X, Peng L, et al.
BMC Cancer . 2012 Dec; 12:619. PMID: 23267699
Background: Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key regulator of mitosis and programmed cell death. YM155, a novel molecular targeted agent, suppresses...