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Xiao-Bo Tang

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Articles 21
Citations 416
Followers 0
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Recent Articles
11.
Wu C, Bao H, Tang X, Zhu D
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi . 2009 Jan; 25(2):158-60, 163. PMID: 19174014
Aim: To construct a prokaryotic plasmid expressing human carboxyles-terases-II (hCE-II ), purify the recombinant protein and investigate the rabbit polyclonal antibody against hCE-II . Methods: A recombinant plasmid expressing pGEX-4T-1-hCE-II...
12.
Wacker J, Feller D, Tang X, DeFino M, Namkung Y, Lyssand J, et al.
J Biol Chem . 2008 Sep; 283(45):31068-78. PMID: 18772143
The G-protein-coupled receptor (GPCR) GPR54 is essential for the development and maintenance of reproductive function in mammals. A point mutation (L148S) in the second intracellular loop (IL2) of GPR54 causes...
13.
Lyssand J, DeFino M, Tang X, Hertz A, Feller D, Wacker J, et al.
J Biol Chem . 2008 May; 283(27):18792-800. PMID: 18468998
Hypertension is a cardiovascular disease associated with increased plasma catecholamines, overactivation of the sympathetic nervous system, and increased vascular tone and total peripheral resistance. A key regulator of sympathetic nervous...
14.
Poppe H, Rybalkin S, Rehmann H, Hinds T, Tang X, Christensen A, et al.
Nat Methods . 2008 Apr; 5(4):277-8. PMID: 18376388
No abstract available.
15.
Zhang Y, Liu Y, Yang J, Liu X, Chi J, Gao J, et al.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi . 2008 Jan; 24(1):45-8. PMID: 18177618
Aim: To prepare rabbit polyclonal antibodies (pAb) and mouse monoclonal antibodies (mAbs) against human clusterin(CLU) and characterize these antibodies' properties. Methods: CLU fragment was amplified from human liver cDNA library,...
16.
Wu Z, Tang X, Wang Z, Ji H, Yu L, Liu H, et al.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi . 2007 Feb; 23(2):148-51. PMID: 17286910
Aim: To prepare monoclonal antibody(mAb) against human carboxylesterases-II (hCE-II) and characterize its properties. Methods: BALB/c mice were immunized with human liver microsome protein which contained hCE-II. The mAb was prepared...
17.
Ye H, Bi H, Lu C, Tang X, Zhu D
Sheng Li Xue Bao . 2005 Oct; 57(5):612-8. PMID: 16220200
15-hydroxyeicosatetraenoic acid (15-HETE) plays an important role in hypoxia-induced pulmonary vasoconstriction. Release of nitric oxide (NO) is apparently decreased and activity of endothelial nitric oxide synthase (eNOS) is impaired in...
18.
Lu C, Ye H, Tang X, Zhu D
Sheng Li Xue Bao . 2005 Oct; 57(5):605-11. PMID: 16220199
Hypoxia-induced 15-hydroxyeicosatetraenoic acid (15-HETE) is an essential mediator to constrict pulmonary arteries (PA). The signaling pathway involved in 15-HETE-induced PA vasoconstriction remains obscure. The aim of the present study was...
19.
Wu A, Tang X, Martinez S, Ikeda K, Beavo J
J Biol Chem . 2004 Jun; 279(36):37928-38. PMID: 15210692
Binding of cGMP to the GAF-B domain of phosphodiesterase 2A allosterically activates catalytic activity. We report here a series of mutagenesis studies on the GAF-B domain of PDE2A that support...
20.
Rybalkin S, Rybalkina I, Shimizu-Albergine M, Tang X, Beavo J
EMBO J . 2003 Jan; 22(3):469-78. PMID: 12554648
cGMP-specific, cGMP-binding phosphodiesterase (PDE5) regulates such physiological processes as smooth muscle relaxation and neuronal survival. PDE5 contains two N-terminal domains (GAF A and GAF B), but the functional roles of...