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Xian-Jun Yu

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Articles 109
Citations 1861
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Recent Articles
11.
Wang T, Qin Y, Ye Z, Jing D, Fan G, Liu M, et al.
Acta Pharmacol Sin . 2023 Apr; 44(8):1536-1548. PMID: 37012494
Autophagy-lysosome system plays a variety of roles in human cancers. In addition to being implicated in metabolism, it is also involved in tumor immunity, remodeling the tumor microenvironment, vascular proliferation,...
12.
Li H, Jiang W, Zhang S, Li P, Li T, Jin W, et al.
Oncogene . 2023 Mar; 42(18):1453-1465. PMID: 36922676
We aimed to investigate the protumor mechanisms of platelets in pancreatic ductal adenocarcinoma (PDAC). Serum samples were collected from 656 PDAC patients and 3105 healthy people, and a Panx1 knockout...
13.
Ma M, Cheng H, Chen Y, Yu X, Liu C
Hepatobiliary Pancreat Dis Int . 2023 Jan; 22(2):147-153. PMID: 36690522
Background: Open pancreaticoduodenectomy (OPD) with portal or superior mesenteric vein resection and reconstruction has been applied in pancreatic cancer patients with tumor infiltration or adherence. However, it is controversial whether...
14.
Song C, Hu Y, Mang Z, Ye Z, Chen H, Jing D, et al.
Acta Pharmacol Sin . 2022 Oct; 44(4):865-876. PMID: 36284209
Hernandezine (Her) is a bisbenzylisoquinoline alkaloid extracted from the traditional Chinese herbal medicine Thalictrum glandulosissimum. Evidence shows that Her is a natural agonist of adenosine monophosphate (AMP)-activated protein kinase (AMPK)...
15.
Hu H, Li Z, Chen K, Liu M, Ye Z, Chen X, et al.
Front Surg . 2022 Oct; 9:970178. PMID: 36277293
Background: Pancreatic neuroendocrine tumors (pNETs) and solid pseudopapillary tumors (SPTs) are two of the most common pancreatic neoplasms with different treatment procedures. However, the broad heterogeneity of pNETs and SPTs...
16.
Lu S, Hua J, Liu J, Wei M, Liang C, Meng Q, et al.
Transl Oncol . 2022 Aug; 25:101524. PMID: 36041293
Pyroptosis is a form of programmed cell death associated with inflammatory alterations. However, the intrinsic mechanisms and underlying correlation of pyroptosis-related lncRNAs (PRLs) in pancreatic ductal adenocarcinoma (PDAC) remain unclear....
17.
Zhang W, Gao H, Liu W, Qin Y, Ye Z, Lou X, et al.
Front Endocrinol (Lausanne) . 2022 Aug; 13:941210. PMID: 36034463
Background: Tumor grade determined by the Ki67 index is the best prognostic factor for pancreatic neuroendocrine tumors (PanNETs). However, we often observe that the grade of metastases differs from that...
18.
Han X, Zhang W, Gao H, Li T, Xu H, Li H, et al.
J Clin Lab Anal . 2022 May; 36(7):e24517. PMID: 35622458
Background: The selective pressure imposed by chemotherapy creates a barrier to tumor eradication and an opportunity for metastasis and recurrence. As a newly discovered stemness marker of pancreatic ductal adenocarcinoma...
19.
Li T, Jin K, Li H, Ye L, Li P, Jiang B, et al.
Cancer Lett . 2022 Jan; 530:142-155. PMID: 35077803
Pancreatic ductal adenocarcinoma (PDAC) usually presents infrequent infiltration of T lymphocytes. The known immune-checkpoint inhibitors to date focus on activating T cells and manifest limited effectiveness in PDAC. SIGLEC15 was...
20.
Gao S, Wang G, Wang L, Feng L, Zhou Y, Yu X, et al.
Cell Calcium . 2022 Jan; 102:102527. PMID: 35026540
CACNA1E is a gene encoding the ion-conducting α1 subunit of R-type voltage-dependent calcium channels, whose roles in tumorigenesis remain to be determined. We previously showed that CACNA1E was significantly mutated...