Xevi Biarnes
Overview
Explore the profile of Xevi Biarnes including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
593
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0
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Recent Articles
1.
Vega A, Planas A, Biarnes X
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940748
The growing demand for efficient, selective, and stable enzymes has fueled advancements in computational enzyme engineering, a field that complements experimental methods to accelerate enzyme discovery. With a plethora of...
2.
Rabada Y, Bosch-Sanz O, Biarnes X, Pedreno J, Caveda L, Sanchez-Garcia D, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000111
A new family of antifibrinolytic drugs has been recently discovered, combining a triazole moiety, an oxadiazolone, and a terminal amine. Two of the molecules of this family have shown activity...
3.
Skulj S, Kozic M, Barisic A, Vega A, Biarnes X, Piantanida I, et al.
Comput Struct Biotechnol J
. 2024 Feb;
23:742-751.
PMID: 38298178
Peroxidases are essential elements in many biotechnological applications. An especially interesting concept involves split enzymes, where the enzyme is separated into two smaller and inactive proteins that can dimerize into...
4.
Nin-Hill A, Ardevol A, Biarnes X, Planas A, Rovira C
Chemistry
. 2023 Oct;
29(70):e202302555.
PMID: 37804517
Bacterial β-glycosidases are hydrolytic enzymes that depolymerize polysaccharides such as β-cellulose, β-glucans and β-xylans from different sources, offering diverse biomedical and industrial uses. It has been shown that a conformational...
5.
Guidi C, Biarnes X, Planas A, De Mey M
Biotechnol Adv
. 2022 Dec;
63:108081.
PMID: 36529206
Glycosyltransferases (GT) catalyse the biosynthesis of complex carbohydrates which are the most abundant group of molecules in nature. They are involved in several key mechanisms such as cell signalling, biofilm...
6.
Bosch-Sanz O, Rabada Y, Biarnes X, Pedreno J, Caveda L, Balcells M, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499270
Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such as general surgery...
7.
Cotrina E, Oliveira A, Llop J, Quintana J, Biarnes X, Cardoso I, et al.
Environ Res
. 2022 Nov;
217:114836.
PMID: 36400222
Several anthropogenic contaminants have been identified as competing with the thyroid hormone thyroxine (T) for binding to transport proteins as transthyretin (TTR). This binding can potentially create toxicity mechanisms posing...
8.
Lansky S, Salama R, Biarnes X, Shwartstein O, Schneidman-Duhovny D, Planas A, et al.
Commun Biol
. 2022 May;
5(1):465.
PMID: 35577850
AbnA is an extracellular GH43 α-L-arabinanase from Geobacillus stearothermophilus, a key bacterial enzyme in the degradation and utilization of arabinan. We present herein its full-length crystal structure, revealing the only...
9.
Cuxart I, Coines J, Esquivias O, Faijes M, Planas A, Biarnes X, et al.
ACS Catal
. 2022 Apr;
12(8):4737-4743.
PMID: 35465242
lacto--biosidase (LnbB) is a critical enzyme for the degradation of human milk oligosaccharides in the gut microbiota of breast-fed infants. Guided by recent crystal structures, we unveil its molecular mechanism...
10.
Grifoll-Romero L, Sainz-Polo M, Albesa-Jove D, Guerin M, Biarnes X, Planas A
J Biol Chem
. 2019 Nov;
294(50):19066-19080.
PMID: 31690626
PdaC (PdaC) is a membrane-bound, multidomain peptidoglycan deacetylase acting on -acetylmuramic acid (MurNAc) residues and conferring lysozyme resistance to modified cell wall peptidoglycans. PdaC contains a C-terminal family 4 carbohydrate...