Xavier Nassif
Overview
Explore the profile of Xavier Nassif including associated specialties, affiliations and a list of published articles.
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Articles
142
Citations
4847
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0
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Recent Articles
1.
Wuckelt M, Laurent A, Mouville C, Meyer J, Jamet A, Lecuyer H, et al.
Appl Environ Microbiol
. 2024 Aug;
90(9):e0088024.
PMID: 39140741
The efficient natural transformation of allows the rapid construction of bacterial mutants in which the genes of interest are interrupted or replaced by antibiotic-resistance cassettes. However, this proved to be...
2.
Ziveri J, Le Guennec L, Dos Santos Souza I, Barnier J, Walter S, Diallo Y, et al.
Nat Microbiol
. 2024 Aug;
9(9):2434-2447.
PMID: 39103571
Loss of endothelial integrity and vascular leakage are central features of sepsis pathogenesis; however, no effective therapeutic mechanisms for preserving endothelial integrity are available. Here we show that, compared to...
3.
Wu S, Coureuil M, Nassif X, Tautz L
Sci Rep
. 2023 Dec;
13(1):22015.
PMID: 38086986
Protein phosphorylation is an integral part of many cellular processes, not only in eukaryotes but also in bacteria. The discovery of both prokaryotic protein kinases and phosphatases has created interest...
4.
Fourgeaud J, Regnault B, Ok V, Da Rocha N, Sitterle E, Mekouar M, et al.
Lancet Microbe
. 2023 Dec;
5(1):e52-e61.
PMID: 38048804
Background: Metagenomic next-generation sequencing (mNGS) allows untargeted identification of a broad range of pathogens, including rare or novel microorganisms. Despite the recognition of mNGS as a valuable diagnostic tool for...
5.
Wu S, Coureuil M, Nassif X, Tautz L
Res Sq
. 2023 Sep;
PMID: 37693380
Protein phosphorylation is an integral part of many cellular processes, not only in eukaryotes but also in bacteria. The discovery of both prokaryotic protein kinases and phosphatases has created interest...
6.
Wu S, Coureuil M, Nassif X, Tautz L
bioRxiv
. 2023 Jun;
PMID: 37292688
Protein phosphorylation is an integral part of many cellular processes, not only in eukaryotes but also in bacteria. The discovery of both prokaryotic protein kinases and phosphatases has created interest...
7.
Implantation of engineered human microvasculature to study human infectious diseases in mouse models
Schonherr-Hellec S, Chatzopoulou E, Barnier J, Atlas Y, Dupichaud S, Guilbert T, et al.
iScience
. 2023 Mar;
26(4):106286.
PMID: 36942053
Animal models for studying human pathogens are crucially lacking. We describe the implantation in mice of engineered human mature microvasculature consisting of endothelial and perivascular cells embedded in collagen hydrogel...
8.
Ramond E, Lepissier A, Ding X, Bouvier C, Tan X, Euphrasie D, et al.
J Infect Dis
. 2022 May;
226(7):1276-1285.
PMID: 35524969
Background: Staphylococcus aureus dominates the lung microbiota of children with cystic fibrosis (CF) and persistent clones are able to establish chronic infection for years, having a direct deleterious impact on...
9.
Barnier J, Meyer J, Kolappan S, Bouzinba-Segard H, Gesbert G, Jamet A, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(45).
PMID: 34725157
utilizes type IV pili (T4P) to adhere to and colonize host endothelial cells, a process at the heart of meningococcal invasive diseases leading to meningitis and sepsis. T4P are polymers...
10.
Barnier J, Euphrasie D, Join-Lambert O, Audry M, Schonherr-Hellec S, Schmitt T, et al.
PLoS Pathog
. 2021 Feb;
17(2):e1009299.
PMID: 33592056
Neisseria meningitidis (the meningococcus) remains a major cause of bacterial meningitis and fatal sepsis. This commensal bacterium of the human nasopharynx can cause invasive diseases when it leaves its niche...