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Wyatt N Vreeland

Explore the profile of Wyatt N Vreeland including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 596
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Recent Articles
1.
Zheng J, Hong B, Agus J, Tang X, Guo F, Lebrilla C, et al.
Cell Rep Methods . 2025 Jan; 5(1):100962. PMID: 39874947
High-density lipoprotein (HDL) particle diameter distribution is informative in the diagnosis of many conditions, including Alzheimer's disease (AD). However, obtaining an accurate HDL size measurement is challenging. We demonstrated the...
2.
Cavicchi R, Ripple D, Welsh J, Izac J, Peterson A, Goldfain A, et al.
Cytometry A . 2025 Jan; 107(1):45-53. PMID: 39835389
An emulsion of silicone oil droplets in aqueous buffer produces a distinctive series of peaks or resonances in the side scatter histogram in a flow cytometer. As many as 12...
3.
Lehman S, Vreeland W, Blaszczyk A, Adams-Hall S, Ahuja S, Arnaout A, et al.
Hum Gene Ther . 2024 Dec; 36(1-2):36-44. PMID: 39723438
Recombinant adeno-associated virus (AAV) is one of the main viral vector-based gene therapy platforms. AAV is a virus consisting of a ≈25 nm diameter capsid with a ≈4.7 kb cargo...
4.
Lehman S, Benkstein K, Cleveland 4th T, Anderson K, Carrier M, Vreeland W
Langmuir . 2023 Aug; 39(35):12313-12323. PMID: 37603854
Lipid nanoparticles are a generic type of nanomaterial with broad applicability in medicine as drug delivery vehicles. Liposomes are a subtype of lipid nanoparticles and, as a therapeutic platform, can...
5.
DeRose P, Benkstein K, Elsheikh E, Gaigalas A, Lehman S, Ripple D, et al.
Nanomaterials (Basel) . 2022 Sep; 12(18). PMID: 36144906
The number of techniques to measure number concentrations and size distributions of submicrometer particles has recently increased. Submicrometer particle standards are needed to improve the accuracy and reproducibility of these...
6.
Mateescu B, Jones J, Alexander R, Alsop E, An J, Asghari M, et al.
iScience . 2022 Aug; 25(8):104653. PMID: 35958027
The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013-2018),...
7.
Arab T, Mallick E, Huang Y, Dong L, Liao Z, Zhao Z, et al.
J Extracell Vesicles . 2021 Apr; 10(6):e12079. PMID: 33850608
We compared four orthogonal technologies for sizing, counting, and phenotyping of extracellular vesicles (EVs) and synthetic particles. The platforms were: single-particle interferometric reflectance imaging sensing (SP-IRIS) with fluorescence, nanoparticle tracking...
8.
Lehman S, Karageorgos I, Filteau J, Vreeland W
J Pharm Sci . 2021 Jan; 110(5):1948-1957. PMID: 33453208
Protein aggregation can affect the quality of protein-based therapeutics. Attempting to unravel factors influencing protein aggregation involves systematic studies. These studies often include sodium azide or similar preservatives in the...
9.
Nelson B, Maragh S, Ghiran I, Jones J, DeRose P, Elsheikh E, et al.
Nanomedicine (Lond) . 2020 Sep; 15(22):2149-2170. PMID: 32885720
Extracellular vesicles (EVs), such as exosomes and microvesicles, are nonreplicating lipid bilayer particles shed by most cell types which have the potential to revolutionize the development and efficient delivery of...
10.
Defante A, Vreeland W, Benkstein K, Ripple D
J Pharm Sci . 2017 Dec; 107(5):1383-1391. PMID: 29277640
Nanoparticle tracking analysis (NTA) obtains particle size by analysis of particle diffusion through a time series of micrographs and particle count by a count of imaged particles. The number of...